[HTML][HTML] Administration of a co-crystal of tramadol and celecoxib in a 1: 1 molecular ratio produces synergistic antinociceptive effects in a postoperative pain model in …

M Merlos, E Portillo-Salido, A Brenchat, B Aubel… - European Journal of …, 2018 - Elsevier
Drug combination for the treatment of pain is common clinical practice. Co-crystal of
Tramadol-Celecoxib (CTC) consists of two active pharmaceutical ingredients (APIs), namely …