Aims To undertake an individual patient data (IPD) meta‐analysis to assess the impact of
exercise‐based cardiac rehabilitation (ExCR) in patients with heart failure (HF) on mortality …

The Cochrane risk of bias tool (RoB) is a widely used measure for methodological quality of
randomized controlled trials. This paper discusses RoB's rationale and risk of bias domains …

Abstract Objectives Kaplan–Meier survival analysis overestimates cumulative incidence in
competing risks (CRs) settings. The extent of overestimation (or its clinical significance) has …

Background Early initiation of combination antiretroviral therapy (cART), at higher CD4 cell
counts, prevents disease progression and reduces sexual transmission of human …

Network meta-analysis (NMA) is a common approach to summarizing relative treatment
effects from randomized trials with different treatment comparisons. Most NMAs are based …

Literature reviews, and more particularly systematic reviews, are increasingly being
produced and published. The past 40 years have been marked by considerable …

Background Dual therapy (DT) with a ritonavir-boosted PI (PI/r) plus lamivudine has proven
non-inferior (12% margin) to triple therapy (TT) with PI/r plus two nucleos (t) ide reverse …

Editor's note: This article is reprinted from Volume 80-4 (1999) as part of the Revisiting Our
Heritage series. Nearly 20 years ago, one of the earliest articles to appear in a social work …

Background In 2010, a new histopathological classification of ANCA-associated
glomerulonephritis (ANCA-GN) based on four categories (focal, crescentic, mixed, and …

A medicina baseada em evidências (MBE) originou-se da nova ciência resultante da
associação dos métodos da epidemiologia com a pesquisa clínica. Enquanto clínicos e …