The roles of insulin‐like growth factor 2 mRNA‐binding protein 2 in cancer and cancer stem cells

J Cao, Q Mu, H Huang - Stem cells international, 2018 - Wiley Online Library
RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus

PS Plum, D Ulase, E Bollschweiler, SH Chon… - Journal of Cancer …, 2018 - Springer
Purpose Therapeutic decisions in esophageal adenocarcinomas (EAC) restricted to mucosa
(pT1a) or submucosa (pT1b) depend mainly on classic histomorphology-based criteria like …

The expression level of vascular endothelial growth factor receptor-2, vascular endothelial growth factor receptor-3, and insulin-like growth factor II mRNA binding …

O Eronat, O Kandemir, A Onursever - Clinical Cancer Investigation …, 2018 - ccij-online.org
Background: The malignant tumors of the kidney are the most aggressive among urologic
cancers. To treat patients with renal cell carcinoma (RCC), it is important to understand the …

IMP3 expression in NSCLC brain metastases demonstrates its role as a prognostic factor in non-neuroendocrine phenotypes

A Del Gobbo, A Morotti, AE Colombo, V Vaira, G Ercoli… - Medical Oncology, 2018 - Springer
Brain metastases from NSCLC are associated with a poor prognosis, and local radiotherapy
is the most effective therapeutic strategy. The oncofetal protein IMP3 has been studied …

Method for detection of L523S expression in biological samples

KM Sojka, EO Spaulding - US Patent 9,869,678, 2018 - Google Patents
The present invention discloses methods for differentiating between normal or reactive cells
and malignant cells in biological samples comprising: exposing the biological sample to an …