Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction

Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

[HTML][HTML] Prolonged fasting-induced metabolic signatures in human skeletal muscle of lean and obese men

AM Bak, MH Vendelbo, B Christensen, R Viggers… - PloS one, 2018 - journals.plos.org
Insulin resistance is a well-known physiological adaptation to prolonged fasting in healthy
skeletal muscle. Obesity is associated with insulin resistance and metabolic inflexibility in …

[PDF][PDF] The effects of the ketogenic diet on psychiatric symptomatology, weight and metabolic dysfunction in schizophrenia patients

J Gilbert-Jaramillo, D Vargas-Pico… - Clin. Nutr …, 2018 - m.script-one.com
Objective: The authors aimed to test the effect of a therapeutic ketogenic diet (KD) on the
psychotic condition, body composition and metabolic dysfunction in schizophrenic patients …

Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women

C Breuker, C Amouzou, O Fabre, K Lambert, P Seyer… - Metabolism, 2018 - Elsevier
Context Toll-like receptor 4 (TLR4) activation contributes to obesity-associated insulin
resistance in skeletal muscles (SM). TLR4 signaling involves two pathways: the myeloid …

Dietary intervention and tissue remodelling

B Liu - 2018 - digital.library.adelaide.edu.au
Increased macrophage infiltration and extracellular matrix deposition in adipose tissue and
skeletal muscle are observed in obesity and associated with insulin resistance. Daily calorie …