Estrogen promotes mandibular condylar fibrocartilage chondrogenesis and inhibits degeneration via estrogen receptor alpha in female mice

JL Robinson, P Soria, M Xu, M Vrana, J Luchetti… - Scientific reports, 2018 - nature.com
Temporomandibular joint degenerative disease (TMJ-DD) is a chronic form of TMJ disorder
that specifically afflicts people over the age of 40 and targets women at a higher rate than …

Functional adaptation of bone: the mechanostat and beyond

P Pivonka, A Park, MR Forwood - Multiscale mechanobiology of bone …, 2018 - Springer
The conceptual model of the mechanostat proposed by Harold Frost in 1983 is among the
most significant contributions to musculoskeletal research today. This model states that bone …

Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene

S Posritong, JM Hong, PP Eleniste, PW McIntyre… - Molecular and cellular …, 2018 - Elsevier
Bone remodeling is controlled by the actions of bone-degrading osteoclasts and bone-
forming osteoblasts (OBs). Aging and loss of estrogen after menopause affects bone mass …

Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression

B Gharibi, MS Ghuman, G Cama… - Molecular and cellular …, 2018 - Elsevier
The osteoporosis-resistant nature of skull bones implies inherent differences exist between
their cellular responses and those of other osteoporosis-susceptible skeletal sites …

The combination of icariin and constrained dynamic loading stimulation attenuates bone loss in ovariectomy‐induced osteoporotic mice

QS Wang, GF Wang, YR Lu, YL Cui, H Li… - Journal of …, 2018 - Wiley Online Library
Osteoporosis is a disease characterized by low bone mass and progressive destruction of
bone microstructure, resulting in increasing the risk of fracture. Icariin (ICA) as a …

Decreased local and systemic levels of sFRP3 protein in osteosarcoma patients

D Bravo, A Salduz, KL Shogren, MN Okuno, JL Herrick… - Gene, 2018 - Elsevier
Osteosarcoma is a malignant bone tumor that occurs mainly in children and adolescents.
Because Wnt signaling has been implicated in the pathogenesis of osteosarcoma, we have …

Estrogen-induced Tgfbr1 and Bmpr1a expression repressed via estrogen receptor beta in MC3T3-E1 cells

HL He, C Liu, BX Li, CQ Wang, HT Li… - Chinese Medical …, 2018 - journals.lww.com
Background: Estrogen, as an important hormone in human physiological process, is closely
related to bone metabolism. The aim of this study was to investigate the mechanism of …

Sex and Sex Hormones in Tissue Homeostasis

J Lechner, G Gstraunthaler - Homeostasis-An Integrated Vision, 2018 - books.google.com
Women are not small men. Sex-specific differences do not only affect the classical target
organs of sexual differentiation and reproduction, but have been found to involve most, if not …

Relationship between impaired forearm endothelial function and osteoporosis in Tunisian postmenopausal women: Serum lipids or others factors?

K Baccouche, H Debbabi, S Belghali, N Elamri… - Journal of Indian …, 2018 - Elsevier
Aims Recent research suggests that bone loss and vascular endothelial dysfunction are
functionally interwoven in postmenopausal women. The aim of our study was to assess the …