Chemokines and their receptors play an important role in the recruitment, activation and
differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9 …

Immunotherapy for skin malignancies has ushered in a new era for cancer treatments by
demonstrating unprecedented durable responses in the setting of metastatic Melanoma …

Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent inherited
nephropathy. To date, therapies alleviating the disease have largely focused on targeting …

Background The poor prognosis of colorectal cancer (CRC) largely results from local
invasion and tumor metastases. Epithelial-mesenchymal transition (EMT) is a key step in the …

The aim of this narrative review is to highlight the role of CXCL9 in Ulcerative Colitis (UC), in
order to understand the mechanism underlying the inflammation in UC and to investigate …

To assess the fetal neuroprotective potential of progesterone using a well‐validated mouse
model of lipopolysaccharide (LPS)‐induced intrauterine inflammation (IUI). Embryonic day …

Monokine induced by interferon (IFN)-γ (MIG)/chemokine (CXC motif) ligand 9 (CXCL) 9 is
involved in the pathogenesis of psoriatic arthritis (PsA). It was demonstrated that both blood …

Sarcoidosis is a systemic inflammatory disease, affecting any organ, and that can be
discovered by accident in approximately 5% of cases. High levels of the type-1 helper (Th1) …

The importance of the Type-1 helper immune response in the development of Vitiligo (Vit),
and of chemokine receptor (CXCR) 3 receptor and its chemokine monokine induced by …

Several studies have proposed in Systemic sclerosis (SSc) patients that the monokine
induced by interferon (IFN)-γ (MIG)/chemokine receptor (CXCR) 3 axis has a determinant …