Recent advances in smart hydrogels for biomedical applications: From self-assembly to functional approaches

NN Ferreira, LMB Ferreira, VMO Cardoso… - European Polymer …, 2018 - Elsevier
This review discusses basic aspects used to control the architecture and functional
properties of smart hydrogels. The introduction briefly outlines what has been accomplished …

Recent development and biomedical applications of self-healing hydrogels

Y Wang, CK Adokoh, R Narain - Expert Opinion on Drug Delivery, 2018 - Taylor & Francis
Introduction: Hydrogels are of special importance, owing to their high-water content and
various applications in biomedical and bio-engineering research. Self-healing properties is …

Core–shell microneedle gel for self-regulated insulin delivery

J Wang, Y Ye, J Yu, AR Kahkoska, X Zhang, C Wang… - ACS …, 2018 - ACS Publications
A bioinspired glucose-responsive insulin delivery system for self-regulation of blood glucose
levels is desirable for improving health and quality of life outcomes for patients with type 1 …

Structure–reactivity relationships in boronic acid–diol complexation

WLA Brooks, CC Deng, BS Sumerlin - ACS omega, 2018 - ACS Publications
Boronic acids have found widespread use in the field of biomaterials, primarily through their
ability to bind with biologically relevant 1, 2-and 1, 3-diols, including saccharides and …

Nanoengineered colloidal inks for 3D bioprinting

CW Peak, J Stein, KA Gold, AK Gaharwar - Langmuir, 2018 - ACS Publications
Nanoengineered hydrogels offer the potential to design shear-thinning bioinks for three-
dimensional (3D) bioprinting. Here, we have synthesized colloidal bioinks composed of disk …

Dynamic bonds between boronic acid and alginate: hydrogels with stretchable, self-healing, stimuli-responsive, remoldable, and adhesive properties

SH Hong, S Kim, JP Park, M Shin, K Kim… - …, 2018 - ACS Publications
For the increasing demand of soft materials with wide ranges of applications, hydrogels
have been developed exhibiting variety of functions (eg, stretchable, self-healing, stimuli …

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade‐Triggered Insulin Delivery

Y Zhang, J Wang, J Yu, D Wen, AR Kahkoska, Y Lu… - Small, 2018 - Wiley Online Library
Self‐regulating glucose‐responsive insulin delivery systems have great potential to improve
clinical outcomes and quality of life among patients with diabetes. Herein, an H2O2‐labile …

Mechano‐based transductive sensing for wearable healthcare

T Wang, H Yang, D Qi, Z Liu, P Cai, H Zhang, X Chen - Small, 2018 - Wiley Online Library
Wearable healthcare presents exciting opportunities for continuous, real‐time, and
noninvasive monitoring of health status. Even though electrochemical and optical sensing …

Injectable dynamic covalent hydrogels of boronic acid polymers cross-linked by bioactive plant-derived polyphenols

Z Huang, P Delparastan, P Burch, J Cheng… - Biomaterials …, 2018 - pubs.rsc.org
We report here the development of hydrogels formed at physiological conditions using PEG
(polyethylene glycol) based polymers modified with boronic acids (BAs) as backbones and …

Synthesis of hydrogel-bearing phenylboronic acid moieties and their applications in glucose sensing and insulin delivery

T Elshaarani, H Yu, L Wang, RS Ullah… - Journal of Materials …, 2018 - pubs.rsc.org
In past few years, phenylboronic acids (PBAs) have attracted researcher's attention due to
their unique responsiveness towards diol-containing molecules such as glucose. This …