Glucagon-like peptide-1 (GLP-1) released from gut enteroendocrine cells controls meal-
related glycemic excursions through augmentation of insulin and inhibition of glucagon …

Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an
invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They …

Abstract γδ T cells are situated at barrier sites and guard the body from infection and
damage. However, little is known about their roles outside of host defense in nonbarrier …

The incretin hormone Glucagon-Like Peptide-1 (GLP-1) is best known for its “incretin effect”
in restoring glucose homeostasis in diabetics, however, it is now apparent that it has a …

The intestinal epithelium must balance efficient absorption of nutrients with partitioning
commensals and pathogens from the bodies' largest immune system. If this crucial barrier …

Immune cells were recently found to have an unexpected involvement in controlling the
thermogenic activity of brown and beige adipose tissue. Here, we review how macrophages …

Ageing, like obesity, is often associated with alterations in metabolic and inflammatory
processes resulting in morbidity from diseases characterised by poor metabolic control …

Adipose tissue performs immunoregulatory functions in addition to fat storage. Various T
cells in different fat depots either help maintain metabolic homeostasis under healthy …

The precise steps of iNKT subset differentiation in the thymus and periphery have been
controversial. We demonstrate here that the small proportion of thymic iNKT and mucosal …

Metabolic surgery is the best treatment for long-term weight loss maintenance and
comorbidity control. Metabolic operations were originally intended to change anatomy to …