Regulation of antimicrobial pathways by endogenous heat shock proteins in gastrointestinal disorders
E Finlayson-Trick, J Connors, A Stadnyk… - Gastrointestinal …, 2018 - mdpi.com
Heat shock proteins (HSPs) are essential mediators of cellular homeostasis by maintaining
protein functionality and stability, and activating appropriate immune cells. HSP activity is …
protein functionality and stability, and activating appropriate immune cells. HSP activity is …
Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1)
A Leja-Szpak, K Nawrot-Porąbka, M Góralska… - Pharmacological …, 2018 - Springer
Background Gemcitabine is a standard chemotherapeutic agent for patients suffering from
pancreatic cancer. However, the applied therapy is not effective due to the resistance of …
pancreatic cancer. However, the applied therapy is not effective due to the resistance of …
The protein–protein interaction network and clinical significance of heat-shock proteins in esophageal squamous cell carcinoma
H Sun, X Cai, H Zhou, X Li, Z Du, H Zou, J Wu, L Xie… - Amino Acids, 2018 - Springer
Abstract Heat-shock proteins (HSPs), one of the evolutionarily conserved protein families,
are widely found in various organisms, and play important physiological functions …
are widely found in various organisms, and play important physiological functions …
Enzyme-treated asparagus extract down-regulates heat shock protein 27 of pancreatic cancer cells
T Shimada, Y Nanimoto, B Baron, T Kitagawa… - in vivo, 2018 - iv.iiarjournals.org
Background/Aim: From the standpoint of cancer therapy, it is valuable to enhance the
anticancer effects of chemotherapy. Our previous reports revealed that up-regulation of heat …
anticancer effects of chemotherapy. Our previous reports revealed that up-regulation of heat …
[HTML][HTML] The loss of CD44 and HSP70 overexpression is related to aggressive clinicopathologic factors in prostate cancer
JA Baek, JH Choi, MJ Gu - International journal of clinical and …, 2018 - ncbi.nlm.nih.gov
Prostate cancer (PC) is the most common cancer in men with biologically highly
heterogeneous clinical outcomes despite early detection. Therefore, the identification of …
heterogeneous clinical outcomes despite early detection. Therefore, the identification of …
Role of intestinal Hsp70 in barrier maintenance: contribution of milk to the induction of Hsp70. 2
RM Rentea, Y Guo, X Zhu, MW Musch… - Pediatric surgery …, 2018 - Springer
Background Necrotizing enterocolitis (NEC) is a gastrointestinal disease of complex etiology
resulting in devastating systemic inflammation and often death in premature newborns. We …
resulting in devastating systemic inflammation and often death in premature newborns. We …