Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …

A central aspect of the pathogenesis of gout is elevated urate concentrations, which lead to
the formation of monosodium urate crystals. The clinical features of gout result from an …

Colchicine is an ancient medication that is currently approved for the treatment of gout and
FMF. However, colchicine has a wide range of anti-inflammatory activities, and studies …

Background In the UK, gout management is suboptimum, with only 40% of patients receiving
urate-lowering therapy, usually without titration to achieve a target serum urate …

Аннотация В 2015 г. экспертами, представляющими различные врачебные ассоциации
России, были разработаны клинические рекомендации «Рациональное применение …

Abstract Drug-induced calculi represent 1–2% of all renal calculi. The drugs reported to
produce calculi may be divided into two groups. The first one includes poorly soluble drugs …

Objective In addition to the controversy regarding the association of hyperuricemia with
cardiovascular disease (CVD) mortality, few studies have examined the impact of a low uric …

The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …

Objective In the management of chronic gout, a large proportion of patients need long-term
management with urate lowering therapy (ULT). This study reviews medication adherence to …

Several epidemiological studies report a positive correlation between hyperuricemia and
metabolic syndrome (MetS) in adults, which hyperuricemic subjects seem to more easily …