[HTML][HTML] Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells

JK Millet, GR Whittaker - Virology, 2018 - Elsevier
During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …

Priming time: how cellular proteases arm coronavirus spike proteins

M Hoffmann, H Hofmann-Winkler… - Activation of viruses by host …, 2018 - Springer
Coronaviruses are enveloped RNA viruses that infect mammals and birds. Infection of
humans with globally circulating human coronaviruses is associated with the common cold …

Membrane-anchored serine proteases: host cell factors in proteolytic activation of viral glycoproteins

E Böttcher-Friebertshäuser - Activation of Viruses by Host Proteases, 2018 - Springer
Over one third of all known proteolytic enzymes are serine proteases. Among these, the
trypsin-like serine proteases comprise one of the best characterized subfamilies due to their …

Lysosomal proteases are a determinant of coronavirus tropism

Y Zheng, J Shang, Y Yang, C Liu, Y Wan… - Journal of …, 2018 - Am Soc Microbiol
Cell entry by coronaviruses involves two principal steps, receptor binding and membrane
fusion; the latter requires activation by host proteases, particularly lysosomal proteases …

[HTML][HTML] SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus)

N Van Doremalen, A Schäfer, VD Menachery, M Letko… - Viruses, 2018 - mdpi.com
Severe acute respiratory syndrome (SARS)-like WIV1-coronavirus (CoV) was first isolated
from Rhinolophus sinicus bats and can use the human angiotensin converting enzyme 2 …

[HTML][HTML] Conséquences neurologiques des clivages de la glycoprotéine S du coronavirus neuroinvasif humain OC43

A Le Coupanec - 2018 - search.proquest.com
Les coronavirus humains (HCoV) sont des virus respiratoires opportunistes infectant les
voies respiratoires supérieures pour y provoquer le rhume. Ces virus peuvent également …