The NT5E (CD73) molecule represents an ecto-5′-nucleotidase expressed on the cell
surface of various cell types. Hydrolyzing extracellular adenosine monophosphate into …

Motivation RNA-binding proteins (RBPs) take over 5–10% of the eukaryotic proteome and
play key roles in many biological processes, eg gene regulation. Experimental detection of …

Mutated or dysregulated DDX3 participates in the progression and metastasis of cancer via
its multiple roles in regulating gene expression and cellular signaling. Here, we show that …

RNA-binding proteins (RBPs) are expressed broadly during both development and
malignant transformation, yet their mechanistic roles in epithelial homeostasis or as drivers …

ABSTRACT RNA binding proteins mediate global regulation at the level of transcriptome
and translatome of a cell. We studied the global level expression changes regulated by …

ABSTRACT RNA-protein interactions (RPIs) play a very important role in a wide range of
post-transcriptional regulations, and identifying whether a given RNA-protein pair can form …

Background Characterizing the binding preference of RNA-binding proteins (RBP) is
essential for us to understand the interaction between an RBP and its RNA targets, and to …

During the last decade, the study of mRNA decay has largely benefited from an increasing
number of high-throughput assays that emerged from developments in next generation …

Summary Background Prader Willi Syndrome (PWS) is a syndromic form of obesity caused
by a chromosomal aberration on chromosome 15q11. 2–q13. Patients with a comparable …

Post-transcriptional regulation (PTR) of gene expression is a powerful determinant of protein
levels and cellular phenotypes. The 5'and 3'untranslated regions of the mRNA (UTRs) …