Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …

Idiopathic pulmonary fibrosis (IPF) is an inexorably progressive lung disease of unknown
origin. Prognosis is poor, with limited treatment options available, and the median survival …

Epithelial mesenchymal transition (EMT) is a key progression that promotes pulmonary
fibrosis (PF). Numb, a phosphotyrosine-binding domain (PTB) protein, is implicated with …

Silicosis is one of the typical forms of pneumoconiosis characterized by abnormal
proliferation of fibroblasts and deposition of extracellular matrix. Recent findings have shown …

Acute exacerbations and worsening of idiopathic pulmonary fibrosis (IPF) have been
associated with exposure to ozone (O3), nitrogen dioxide (NO2) and particulate matter, but …

Background Pulmonary fibrosis is a multifaceted disease with high mortality and morbidity,
and it is commonly nonresponsive to conventional therapy. Purpose We explore the …

Pulmonary fibrosis (PF) is a chronic, progressive lung disease, characterized by excessive
matrix formation, destruction of the normal lung architecture, dysfunction and finally death …

Pulmonary fibrosis (PF) is a chronic and ultimately fatal interstitial lung disease of various
causes. The advent of nintedanib and pirfenidone provides treatment options for PF patients …

Endothelial cell injury and subsequent inflammation play pivotal roles in the pathogenesis of
pulmonary fibrosis, a progressive and fatal disorder. We found previously that salvianolic …

Background Idiopathic pulmonary fibrosis (IPF), a chronic, progressive, fibrosing interstitial
lung disease, is associated with extremely poor prognosis, and lacks effective treatment. The …