One potential target for cancer therapeutics is the tumor suppressor p53, which is mutated in
more than 50% of malignant tumors. Loss of function (LoF), dominant negative (DN) and …

Certain lifestyles, such as unhealthy eating habits, are associated with an increased risk for
several diseases, including cancer. Recently, some naturally occurring compounds, such as …

Seventeen endophytic fungi were isolated from various tissues of Cassia fistula and the
ethyl acetate extracts obtained from 21-day cultures of all the endophytic fungal isolates …

The aim of this study was to evaluate the cytotoxicity of a series of seven 4′-methylthio-
trans-stilbene derivatives against cancer cells: MCF7 and A431 in comparison with non …

This study was designed to investigate the mode of action of trabectedin in myelomonocytic
leukemia cells by applying systems biology approaches to mine gene expression profiling …

Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of
biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic …

Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this
project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles …

Transcription factor c-myc is frequently amplified/overexpressed in human cancers. One
event c-myc controls is metabolic reprogramming or the addiction for glucose and/or …

Three main enzymes involved in the enzymatic antioxidant system include superoxide
dismutase (SOD), catalase, and glutathione peroxidase. SODs are highly inducible …

The aim of this study was to evaluate the cytotoxicity of a series of seven 40-methylthio-
transstilbene derivatives against cancer cells: MCF7 and A431 in comparison with non …