Physiological and biological responses to short-term intermittent hypobaric hypoxia exposure: from sports and mountain medicine to new biomedical applications

G Viscor, JR Torrella, L Corral, A Ricart… - Frontiers in …, 2018 - frontiersin.org
In recent years, the altitude acclimatization responses elicited by short-term intermittent
exposure to hypoxia have been subject to renewed attention. The main goal of short-term …

[HTML][HTML] Limitation of maximal heart rate in hypoxia: mechanisms and clinical importance

L Mourot - Frontiers in physiology, 2018 - frontiersin.org
The use of exercise intervention in hypoxia has grown in popularity amongst patients, with
encouraging results compared to similar intervention in normoxia. The prescription of …

[HTML][HTML] Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle

VH Carvalho, AHS Oliveira, LF de Oliveira, RP da Silva… - Redox biology, 2018 - Elsevier
Previous studies have demonstrated that exercise results in reactive aldehyde production
and that β-alanine supplementation increases carnosine content in skeletal muscle …

Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle

W Ji, L Wang, S He, L Yan, T Li, J Wang, ANT Kong… - PLoS …, 2018 - journals.plos.org
Background Hypoxia training enhances the endurance capacity of athletes. This response
may in part be attributed to the hypoxia-induced increase in antioxidant capacity in skeletal …

Effects of high-intensity interval training under normobaric hypoxia on cardiometabolic risk markers in overweight/obese women

A Camacho-Cardenosa… - … Altitude Medicine & …, 2018 - liebertpub.com
Promising benefits on cardiometabolic risk factors have been reported with prolonged
programs of cyclic hypoxia. The aim of this study was to examine whether cyclic hypoxia …

Hypobaric hypoxia-induced learning and memory impairment: elucidating the role of small conductance Ca2+-activated K+ channels

N Kushwah, V Jain, A Dheer, R Kumar, D Prasad… - Neuroscience, 2018 - Elsevier
Hypobaric Hypoxia (HH) is well-known to cause cognitive impairment and synaptic
dysfunction which results in neurodegeneration. Although the role of small conductance …

The MAPK‐activator protein‐1 signaling regulates changes in lung tissue of rat exposed to hypobaric hypoxia

M Singh, S Yadav, M Kumar, S Saxena… - Journal of cellular …, 2018 - Wiley Online Library
This study reports the role of MAPKs (JNK, ERK, and p38), and activator protein‐1 (AP‐1)
transcription factor in the hypobaric hypoxia induced change in lung tissue. Healthy male …

Acute dietary nitrate supplementation does not attenuate oxidative stress or the hemodynamic response during submaximal exercise in hypobaric hypoxia

CR Carriker, P Rombach, BM Stevens… - Applied Physiology …, 2018 - cdnsciencepub.com
The purpose of this study was to investigate changes in oxidative stress, arterial oxygen
saturation (SaO2), blood pressure (BP), and heart rate (HR) during exercise in hypobaric …

Redox‐regulation of haemostasis in hypoxic exercising humans: a randomised double‐blind placebo‐controlled antioxidant study

L Fall, JV Brugniaux, D Davis, CJ Marley… - The Journal of …, 2018 - Wiley Online Library
Key points In vitro evidence has identified that coagulation is activated by increased
oxidative stress, though the link and underlying mechanism in humans have yet to be …

Efeitos do treinamento intervalado de alta intensidade de curto prazo sobre os biomarcadores de estresse oxidativo e danos musculares em ratos

LMV Souza - 2018 - ri.ufs.br
A produção de espécies reativas de oxigênio (EROS) acontece de forma contínua. Dentre
elas o ânion superóxido [O2-] é considerado a principal espécie reativa de oxigênio sendo …