Hypothermia for newborns with hypoxic-ischemic encephalopathy

B Lemyre, V Chau - Paediatrics & child health, 2018 - academic.oup.com
Therapeutic hypothermia is a standard of care for infants≥ 36 weeks gestational age (GA)
with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included …

Intracranial hemorrhage in neonates: A review of etiologies, patterns and predicted clinical outcomes

AP Tan, P Svrckova, F Cowan, WK Chong… - European journal of …, 2018 - Elsevier
Intracranial hemorrhage (ICH) in neonates often results in devastating neurodevelopmental
outcomes as the neonatal period is a critical window for brain development. The …

[HTML][HTML] A novel magnetic resonance imaging score predicts neurodevelopmental outcome after perinatal asphyxia and therapeutic hypothermia

LC Weeke, F Groenendaal, K Mudigonda… - The Journal of …, 2018 - Elsevier
Objective To assess the predictive value of a novel magnetic resonance imaging (MRI)
score, which includes diffusion-weighted imaging as well as assessment of the deep grey …

Plasma biomarkers of brain injury in neonatal hypoxic-ischemic encephalopathy

AN Massaro, YW Wu, TK Bammler, B Comstock… - The Journal of …, 2018 - Elsevier
Objectives To evaluate plasma brain specific proteins and cytokines as biomarkers of brain
injury in newborns with hypoxic-ischemic encephalopathy (HIE) and, secondarily, to assess …

Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy

TI Herrera, L Edwards, WF Malcolm, PB Smith… - Early human …, 2018 - Elsevier
Background Therapeutic hypothermia reduces the risk of death, or moderate to severe
neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic …

[HTML][HTML] Prospective research on infants with mild encephalopathy: the PRIME study

C Prempunpong, LF Chalak, J Garfinkle, B Shah… - Journal of …, 2018 - nature.com
Objective: To determine short-term outcomes of infants with evidence of hypoxia–ischemia
at birth and classified as mild neonatal encephalopathy (NE) at< 6 h of age. Study Design …

Perinatal hypoxic-ischemic brain injury in large animal models: Relevance to human neonatal encephalopathy

RC Koehler, ZJ Yang, JK Lee… - Journal of Cerebral …, 2018 - journals.sagepub.com
Perinatal hypoxia-ischemia resulting in death or lifelong disabilities remains a major clinical
disorder. Neonatal models of hypoxia-ischemia in rodents have enhanced our …

Hypoxic-ischemic encephalopathy and other neonatal encephalopathies

HC Glass - CONTINUUM: Lifelong Learning in Neurology, 2018 - journals.lww.com
PURPOSE OF REVIEW This article puts advances in the field of neurogenetics into context
and provides a quick review of the broad concepts necessary for current practice in …

Head ultrasound in neonatal hypoxic-ischemic injury and its mimickers for clinicians: a review of the patterns of injury and the evolution of findings over time

J Salas, A Tekes, M Hwang, FJ Northington… - Neonatology, 2018 - karger.com
Hypoxic-ischemic injury (HII) of the neonatal brain and resulting clinical hypoxic-ischemic
encephalopathy remains a significant cause of morbidity and mortality in the neonatal …

Therapeutic hypothermia: how can we optimize this therapy to further improve outcomes?

G Natarajan, A Laptook… - Clinics in …, 2018 - perinatology.theclinics.com
Neonatal encephalopathy is a condition of disordered neonatal brain function and is
associated with many risk factors. The incidence of neonatal encephalopathy is estimated to …