The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

[HTML][HTML] Inclusion of females does not increase variability in rodent research studies

AK Beery - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•Female subjects are underrepresented in animal research.•Recent studies
demonstrate that unstaged female rodents are no more variable than males.•Factorial …

The neural mechanisms and circuitry of the pair bond

H Walum, LJ Young - Nature Reviews Neuroscience, 2018 - nature.com
Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

Oxytocin and social relationships: from attachment to bond disruption

OJ Bosch, LJ Young - Behavioral pharmacology of neuropeptides …, 2018 - Springer
Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …

Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives

DS Quintana, KT Smerud, OA Andreassen… - Therapeutic …, 2018 - Taylor & Francis
The neuropeptide oxytocin plays an evolutionarily conserved role in mammalian social
behavior. Despite striking effects on animal social behavior after intracerebroventricular drug …

[HTML][HTML] The monogamy paradox: what do love and sex have to do with it?

CS Carter, AM Perkeybile - Frontiers in ecology and evolution, 2018 - frontiersin.org
Genetic monogamy is rare—at least at the level of a species—and monogamy can exist in
the absence of sexual fidelity. Rather than focusing on mating exclusivity, it has become …

[HTML][HTML] Oxytocin and vasopressin flatten dominance hierarchy and enhance behavioral synchrony in part via anterior cingulate cortex

Y Jiang, ML Platt - Scientific reports, 2018 - nature.com
The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) influence social functions
in many mammals. In humans and rhesus macaques, OT delivered intranasally can promote …

Oxytocin and sex differences in behavior

HK Caldwell - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•There are quantifiable oxytocin-dependent sex differences in behavior.•Sex
differences in behavior are often not associated with structural changes in the oxytocin …

[HTML][HTML] BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior

KR Maynard, JW Hobbs, BDN Phan, A Gupta… - elife, 2018 - elifesciences.org
Brain-derived neurotrophic factor (Bdnf) transcription is controlled by several promoters,
which drive expression of multiple transcripts encoding an identical protein. We previously …

An integrated framework for the role of oxytocin in multistage social decision‐making

M Piva, SWC Chang - American Journal of Primatology, 2018 - Wiley Online Library
Interest in the effects of oxytocin on social behavior has persisted even as an overarching
theory describing these effects has remained largely elusive. Some of the earliest studies on …