Laboratory challenges in the diagnosis of hepatitis E virus

DW Al-Sadeq, AF Majdalawieh… - Journal of Medical …, 2018 - microbiologyresearch.org
Hepatitis E virus (HEV) is an RNA virus that is an important cause of both acute and chronic
hepatitis worldwide. To date, there are eight HEV genotypes that can infect mammals. HEV …

Transmission and epidemiology of hepatitis E virus genotype 3 and 4 infections

HR Dalton, J Izopet - Cold Spring Harbor …, 2018 - perspectivesinmedicine.cshlp.org
Following the introduction of robust serological and molecular tools, our understanding of
the epidemiology of zoonotic hepatitis E virus (HEV) has improved considerably in recent …

[HTML][HTML] Rat hepatitis E virus as cause of persistent hepatitis after liver transplant

S Sridhar, CCY Yip, S Wu, J Cai… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
All hepatitis E virus (HEV) variants reported to infect humans belong to the species
Orthohepevirus A (HEV-A). The zoonotic potential of the species Orthohepevirus C (HEV-C) …

EASL Clinical Practice Guidelines on hepatitis E virus infection

HR Dalton, N Kamar, SA Baylis, D Moradpour… - Journal of …, 2018 - Elsevier
Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality,
representing an important global health problem. Our understanding of HEV has changed …

HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients

D Westhölter, J Hiller, U Denzer, S Polywka, F Ayuk… - Journal of …, 2018 - Elsevier
Background & Aims Routine HEV testing of blood products has recently been implemented
in Great Britain and the Netherlands. The relevance of transfusion-transmitted HEV …

Life cycle and morphogenesis of the hepatitis E virus

K Himmelsbach, D Bender, E Hildt - Emerging microbes & …, 2018 - Taylor & Francis
Hepatitis E virus (HEV) is transmitted primarily via contaminated water and food by the fecal
oral route and causes epidemics in developing countries. In industrialized countries …

[HTML][HTML] Transfusion-transmitted hepatitis E: NAT screening of blood donations and infectious dose

J Dreier, C Knabbe, T Vollmer - Frontiers in medicine, 2018 - frontiersin.org
The risk and importance of transfusion-transmitted hepatitis E virus (TT-HEV) infections by
contaminated blood products is currently a controversial discussed topic in transfusion …

Summary of the British Transplantation Society UK guidelines for hepatitis E and solid organ transplantation

S McPherson, AM Elsharkawy, M Ankcorn, S Ijaz… - …, 2018 - journals.lww.com
The incidence and prevalence of hepatitis E virus (HEV) infection has increased in many
developed countries over the last decade, predominantly due to infection with genotype 3 …

[HTML][HTML] A nationwide retrospective study on prevalence of hepatitis E virus infection in Italian blood donors

E Spada, S Pupella, G Pisani, R Bruni… - Blood …, 2018 - ncbi.nlm.nih.gov
Background In Europe, hepatitis E virus (HEV) infection is mainly a food-borne zoonosis, but
it can also be transmitted by blood transfusion. It is usually a mild and self-limited infection …

[HTML][HTML] Hepatitis E virus treatment and ribavirin therapy: viral mechanisms of nonresponse

D Todt, TL Meister, E Steinmann - Current opinion in virology, 2018 - Elsevier
Highlights•Chronically HEV-infected patients can experience RBV treatment failure.•HEV
genome alterations include SNVs or in-frame insertion in the HVR of ORF1.•These genome …