There are 5 main histological types of thyroid cancers (TCs): papillary, follicular (also known
as differentiated), poorly differentiated, anaplastic (the most aggressive form), and medullary …

Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular
pathology of thyroid tumours originating from follicular cells has greatly advanced in the past …

Purpose: To define the genetic landscape of advanced differentiated and anaplastic thyroid
cancer (ATC) and identify genetic alterations of potential diagnostic, prognostic, and …

Recent studies have shown that miR-146b is the most upregulated microRNA in thyroid
cancer and has a central role in cancer progression through mechanisms that remain largely …

Cancer is generally caused by the molecular alterations which lead to specific mutations.
Advances in molecular biology have provided an impetus to the study of cancers with …

Distant metastases from thyroid cancer of follicular origin are uncommon. Treatment
includes levothyroxine administration, focal treatment modalities with surgery, external …

Of the three RAS oncoproteins, only HRAS is delocalized and inactivated by
farnesyltransferase inhibitors (FTI), an approach yet to be exploited clinically. In this study …

Anaplastic thyroid carcinomas (ATCs) have a high prevalence of BRAF and TP53 mutations.
A trial of vemurafenib in nonmelanoma BRAFV600E-mutant cancers showed significant …

In recent years, thyroid malignances have become more prevalent, especially among
women. The most common sporadic types of thyroid tumors of follicular origin include …

Background The prognosis of poorly differentiated thyroid carcinomas (PDTC) is
heterogeneous though generally poor. The objectives of this study were to identify clinical …