Key Clinical Points Primary Sjögren's Syndrome A diagnosis of primary Sjögren's syndrome
is often made on the basis of a classic triad of symptoms: dryness of the mouth and eyes …

Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

The formation of lymphomononuclear cell infiltrates organising as periductal infiltrates in the
salivary glands of patients with primary Sjogren's syndrome (pSS) is one of the hallmarks of …

Objectives To compare the effects of rituximab versus placebo on salivary gland ultrasound
(SGUS) in primary Sjögren's syndrome (PSS) in a multicentre, multiobserver phase III trial …

Objective To evaluate the clinical efficacy and safety of baminercept, a lymphotoxin β
receptor IgG fusion protein (LT βR‐Ig), for the treatment of primary Sjögren's syndrome (SS) …

Henrik Sjogren used the term “sicca syndrome” to describe the disease that he studied
extensively during his lifetime, beginning with a comprehensive analysis of 19 patients that …

An update on the role of type I interferons in systemic lupu... : Current Opinion in
Rheumatology An update on the role of type I interferons in systemic lupus erythematosus …

Objective EMBODY 1 (ClinicalTrials. gov identifier: NCT 01262365) and EMBODY 2
(ClinicalTrials. gov identifier: NCT 01261793) investigated the efficacy and safety of …

Sjogren's syndrome (SS) is a systemic autoimmune disease that primarily affects the
exocrine glands, resulting in dryness of the eyes and mouth due to lymphocytic infiltration of …

Advances in the understanding of pSS pathogenesis have paved the way for clinical trials
with novel biologic agents targeting immune pathways regulating T/B-cell interactions and …