[HTML][HTML] Preeclampsia: novel mechanisms and potential therapeutic approaches

Z Armaly, JE Jadaon, A Jabbour, ZA Abassi - Frontiers in physiology, 2018 - frontiersin.org
Preeclampsia is a serious complication of pregnancy where it affects 5–8% of all
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …

Reproductive health and pregnancy in women with chronic kidney disease

KS Wiles, C Nelson-Piercy, K Bramham - Nature Reviews Nephrology, 2018 - nature.com
Chronic kidney disease (CKD) is associated with reduced fertility and an increased risk of
adverse pregnancy outcomes. Rates of pre-eclampsia, fetal growth restriction and preterm …

RNAi modulation of placental sFLT1 for the treatment of preeclampsia

AA Turanov, A Lo, MR Hassler, A Makris… - Nature …, 2018 - nature.com
Preeclampsia is a placentally induced hypertensive disorder of pregnancy that is associated
with substantial morbidity and mortality to mothers and fetuses. Clinical manifestations of …

Update on the diagnosis and prognosis of preeclampsia with the aid of the sFlt-1/PlGF ratio in singleton pregnancies

I Herraiz, E Llurba, S Verlohren, A Galindo… - Fetal diagnosis and …, 2018 - karger.com
Preeclampsia (PE) is involved in a group of obstetrical conditions closely related by the
presence of placental dysfunction (PD), which also includes intrauterine growth restriction …

Angiogenic and antiangiogenic factors in preeclampsia

FR Helmo, AMM Lopes, ACDM Carneiro… - … -Research and Practice, 2018 - Elsevier
Background Pre-eclampsia is a multifactorial hypertensive disorder that is triggered by
placental insufficiency and that accounts for up to 15% of maternal deaths. In normal …

[HTML][HTML] Acute kidney injury in pregnancy: the changing landscape for the 21st century

S Rao, B Jim - Kidney international reports, 2018 - Elsevier
Pregnancy-related acute kidney injury (Pr-AKI) remains a large public health problem, with
decreasing incidences in developing countries but seemingly increasing incidences in the …

Preeclampsia-current management and future approach

W Dymara-Konopka, M Laskowska… - Current …, 2018 - ingentaconnect.com
Preeclampsia is one of the most serious pregnancy-specific medical conditions of increasing
incidence. It remains a major cause of maternal and fetal morbidity and mortality. Although …

Cardiovascular sequels during and after preeclampsia

ND Paauw, AT Lely - Sex-Specific Analysis of Cardiovascular Function, 2018 - Springer
Preeclampsia is a pregnancy-specific disorder complicating 2%–8% of pregnancies
worldwide and characterized by de novo development of hypertension and proteinuria …

Angiogenic factors: potential to change clinical practice in pre‐eclampsia?

AS Cerdeira, S Agrawal, AC Staff… - … Journal of Obstetrics …, 2018 - Wiley Online Library
Pre‐eclampsia is a complex disease with significant maternal and fetal morbidity and
mortality. Its syndromic nature makes diagnosis and management difficult. The field is …

[HTML][HTML] Pro-angiogenic therapeutics for preeclampsia

AC Eddy, GL Bidwell III, EM George - Biology of sex differences, 2018 - Springer
Preeclampsia is a pregnancy-induced hypertensive disorder resulting from abnormal
placentation, which causes factors such as sFlt-1 to be released into the maternal …