Near-infrared fluorescent probes for peptidases

J Chin, HJ Kim - Coordination Chemistry Reviews, 2018 - Elsevier
Near-infrared (NIR) fluorescent probes possess a characteristic molecular structure with a
highly conjugated polyene or polynuclear system, thus exhibiting a long emission …

“Probe, Sample, and Instrument (PSI)”: the hat-trick for fluorescence live cell imaging

L Galas, T Gallavardin, M Bénard, A Lehner… - Chemosensors, 2018 - mdpi.com
Cell Imaging Platforms (CIPs) are research infrastructures offering support to a number of
scientific projects including the choice of adapted fluorescent probes for live cell imaging …

Erlotinib-guided self-assembled trifunctional click nanotheranostics for distinguishing druggable mutations and synergistic therapy of nonsmall cell lung cancer

Y Gao, H Zhang, Y Zhang, T Lv, L Zhang… - Molecular …, 2018 - ACS Publications
The outcome of molecular targeted therapies is restricted by the ambiguous molecular
subtypes of nonsmall cell lung cancer (NSCLC), which are difficult to be defined with …

Fluorescent tracking of the endoplasmic reticulum in live pathogenic fungal cells

RI Benhamou, QZ Jaber, IM Herzog… - ACS Chemical …, 2018 - ACS Publications
In fungal cells, the endoplasmic reticulum (ER) harbors several of the enzymes involved in
the biosynthesis of ergosterol, an essential membrane component, making this organelle the …

Far-red fluorescent liposomes for folate receptor-targeted bioimaging

S Dong, JDW Teo, LY Chan, CLK Lee… - ACS Applied Nano …, 2018 - ACS Publications
In this paper, we describe the newly designed liposomes modified with amphiphilic far-red
squaraine dye and folic acid for its application in folate receptor-targeted bioimaging …

Non‐Covalently Pre‐Assembled High‐Performance Near‐Infrared Fluorescent Molecular Probes for Cancer Imaging

SK Shaw, W Liu, CFA Gómez Durán… - … A European Journal, 2018 - Wiley Online Library
New fluorescent molecular probes, which can selectively target specific cell surface
receptors, are needed for microscopy, in vivo imaging, and image guided surgery. The …

High expression of integrin αvβ3 enables uptake of targeted fluorescent probes into ovarian cancer cells and tumors

SK Shaw, CL Schreiber, FM Roland, PM Battles… - Bioorganic & medicinal …, 2018 - Elsevier
The cell line OVCAR-4 was recently ranked as one of the most representative cell lines for
high grade serous ovarian cancer (HGSOC). However, little work has been done to assess …

Alternative fluorophores designed for advanced molecular imaging

LG Freidus, P Pradeep, P Kumar, YE Choonara… - Drug Discovery …, 2018 - Elsevier
Highlights•Alternative and novel fluorophores are required for advanced microscopy
techniques.•NIR fluorophores used to reduce signal to background ratios and improves …

Fluorescent thienothiophene-containing squaraine dyes and threaded supramolecular complexes with tunable wavelengths between 600–800 nm

W Liu, HH McGarraugh, BD Smith - Molecules, 2018 - mdpi.com
A new family of fluorescent thiophene and thienothiophene-containing squaraine dyes is
described with tunable wavelengths that cover the absorption/emission range of 600–800 …

Far‐red‐to NIR‐emitting adamantyl‐functionalized squaraine dye: J‐aggregation, dissociation, and cell imaging

T Liu, X Liu, Y Zhang, MV Bondar… - European Journal of …, 2018 - Wiley Online Library
Squaraine dyes AM‐1′ and AM‐1 bearing adamantyl termini were synthesized and
spectroscopically characterized. AM‐1′ exhibited intense absorption and sharp emission in …