Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

This review brings together observations on the stress-induced regulation of resilience
mechanisms in body tissues. It is argued that the stresses that induce tissue resilience in …

Scope Sulforaphane is an herbal isothiocyanate enriched in cruciferous vegetables. Here,
the authors investigate whether sulforaphane modulates the production of amyloid‐β (Aβ) …

Abstract N-acetyl-L-cysteine (NAC) is a derivative of the sulphur-containing amino acid L-
cysteine with potential anti-aging properties. We studied 3 Drosophila species with contrast …

The role of Sirtuins in brain function is emerging, yet little is known about SIRT5 in this
domain. Our previous work demonstrates that protein kinase C epsilon (PKCε)-induced …

Background We have previously showed that the carotenoid fucoxanthin can increase the
lifespan in Drosophila melanogaster and Caenorhabditis elegans. However, the molecular …

Abstract Naringenin (NGN; 5, 7-dihydroxy-2-(4-hydroxyphenyl)-2, 3-dihydrochromen-4-one;
C 15 H 12 O 5), a flavanone, is found in citrus fruits and has been viewed as an antioxidant …

Antrodia cinnamomea, a precious and unique medical fungus existing exclusively in
Taiwan, exhibits antioxidant and immunomodulatory properties. This study was conducted to …

Mitochondrial dysfunction plays a central role in the pathogenesis of neurodegenerative
diseases such as Parkinson's disease (PD). This study was designed to determine whether …

Altered proteostasis induced by amyloid peptide aggregation and hyperphosphorylation of
tau protein, is a prominent feature of Alzheimer's disease, which highlights the occurrence of …