Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

AP Khawaja, JN Cooke Bailey, NJ Wareham… - Nature …, 2018 - nature.com
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …

Thyroid dysfunction and anemia: a prospective cohort study and a systematic review

C Floriani, M Feller, CE Aubert, K M'Rabet-Bensalah… - Thyroid, 2018 - liebertpub.com
Background: Even though the association between thyroid dysfunction and anemia is
commonly described, it is not known whether it is clinically relevant. This study set out to …

Generalised anxiety disorder and hospital admissions: findings from a large, population cohort study

O Remes, N Wainwright, P Surtees, L Lafortune… - BMJ open, 2018 - bmjopen.bmj.com
Objective Generalised anxiety disorder (GAD) is the most common anxiety disorder in the
general population and has been associated with high economic and human burden …

Understanding the relationship between cognition and death: a within cohort examination of cognitive measures and mortality

SA Hayat, R Luben, N Dalzell, S Moore… - European journal of …, 2018 - Springer
Despite several studies demonstrating an independent and inverse association between
cognition and mortality, the nature of this association still remains unclear. To examine the …

[HTML][HTML] Physical capability predicts mortality in late mid-life as well as in old age: Findings from a large British cohort study

VL Keevil, R Luben, S Hayat, AA Sayer… - Archives of gerontology …, 2018 - Elsevier
Introduction Low physical capability predicts mortality, perhaps by association with co-
morbidity. However, few studies include participants< 70 years old with lower co-morbidity …

A strong sense of coherence associated with reduced risk of anxiety disorder among women in disadvantaged circumstances: British population study

O Remes, NWJ Wainwright, P Surtees, L Lafortune… - BMJ open, 2018 - bmjopen.bmj.com
Objective Many patients receiving medical treatment for anxiety relapse or do not improve.
Research has therefore been turning to coping mechanisms as a way to decrease anxiety …

Patterns of response by sociodemographic characteristics and recruitment methods for women in UK population surveys and cohort studies

SJ Howcutt, AL Barnett, S Barbosa-Boucas… - Women & …, 2018 - Taylor & Francis
Women are an important public health focus, because they are more likely to experience
some social determinants of disease, and they influence family health. Little research has …

Alcohol consumption and future hospital usage: The EPIC-Norfolk prospective population study

R Luben, S Hayat, A Mulligan, M Lentjes, N Wareham… - Plos one, 2018 - journals.plos.org
Background Heavy drinkers of alcohol are reported to use hospitals more than non-drinkers,
but it is unclear whether light-to-moderate drinkers use hospitals more than non-drinkers …

[PDF][PDF] Supplementary Note: 1: Study Populations and Acknowledgements 2: Methods per subfields of prioritization 3: Dopamine pathway look-ups 4: Phenotyping in …

MS Tedja - research.manchester.ac.uk
CREAM (Consortium for Refractive Error and Myopia) was established in 2011 as a
collaboration between studies with data on refractive error which had performed genome …