[HTML][HTML] Anxiolytic properties of compounds that counteract oxidative stress, neuroinflammation, and glutamatergic dysfunction: a review

P Santos, AP Herrmann, E Elisabetsky… - Brazilian Journal of …, 2018 - SciELO Brasil
Objective: Anxiety disorders are highly prevalent and the efficacy of the available anxiolytic
drugs is less than desired. Adverse effects also compromise patient quality of life and …

Understanding antidepressant discontinuation syndrome (ADS) through preclinical experimental models

KN Zabegalov, TO Kolesnikova, SL Khatsko… - European Journal of …, 2018 - Elsevier
Antidepressant drugs are currently one of the most prescribed medications. In addition to
treatment resistance and side effects of antidepressants, their clinical use is further …

Efficacy and safety of agomelatine vs paroxetine hydrochloride in Chinese Han patients with major depressive disorder: a multicentre, double-blind, noninferiority …

YM Yu, KR Gao, H Yu, YF Shen… - Journal of Clinical …, 2018 - journals.lww.com
Purpose The purpose of this study is to investigate the efficacy, safety, and tolerability of
agomelatine and paroxetine in Chinese Han patients with major depressive disorder (MDD) …

[PDF][PDF] Опыт применения вальдоксана при депрессиях, протекающих с когнитивными нарушениями

ВЭ Медведев, АЮ Тер-Исраелян… - … и психиатрии им …, 2018 - researchgate.net
Цель исследования. Оценка эффективности и переносимости монотерапии
вальдоксаном (агомелатин) у больных депрессией с выраженными когнитивными …

Relative short‐term efficacy and acceptability of agomelatine versus vortioxetine in adult patients suffering from major depressive disorder

SH Kennedy, JM Grouin, S Cadour… - Human …, 2018 - Wiley Online Library
Agomelatine and vortioxetine are antidepressants with different mechanisms of action
compared to other pharmaceutical treatment options. The objective of this present analysis …

[HTML][HTML] Molecular basis of atypicality of bupropion inferred from its receptor engagement in nervous system tissues

EJ Kim, K Felsovalyi, LM Young, SV Shmelkov… - …, 2018 - Springer
Despite decades of clinical use and research, the mechanism of action (MOA) of
antidepressant medications remains poorly understood. Selective serotonin reuptake …

[HTML][HTML] Atypical and Treatment-Resistant Depression

S Constantin - 2018 - srconstantin.github.io
Roughly 20-30% of people with depression don't respond to the first antidepressant or two
they try. One of the harder-to-treat subtypes of depression is atypical depression, which …

A Commentary on the Therapeutic Potential of Melatonin and Its

JWH Leung, WKW Lau, BWM Lau… - … Research to a …, 2018 - books.google.com
Melatonin, also known as N-acetyl-5-methoxytryptamine or 5-methoxy-N-acetyltryptamine, is
found in both animals and plants. In mammals, it is mainly produced in the brain by the …

Behandlingsalternativ vid egentlig depression: en jämförelse mellan agomelatin och SSRI/SNRI

N Enbom - 2018 - diva-portal.org
Aim: The aims of the study were to compare the effects on depressive symptoms and
insomnia between agomelatine and SSRIs/SNRIs in adult patients with major depression …

[PDF][PDF] models, European Journal of Pharmacology

ADV Khatsko, OA Yakovlev, TG Amstislavskaya… - 2018 - academia.edu
Antidepressant drugs are currently one of the most prescribed medications. In addition to
treatment resistance and side effects of antidepressants, their clinical use is further …