The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2+ and CCR5+ IFNγ-producing γδT cells in mice

RC Russo, B Savino, M Mirolo… - … of Physiology-Lung …, 2018 - journals.physiology.org
Chemokines coordinate lung inflammation and fibrosis by acting on chemokine receptors
expressed on leukocytes and other cell types. Atypical chemokine receptors (ACKRs) bind …

[HTML][HTML] The atypical chemokine receptor 2 limits renal inflammation and fibrosis in murine progressive immune complex glomerulonephritis

A Bideak, A Blaut, JM Hoppe, MB Müller, G Federico… - Kidney international, 2018 - Elsevier
The atypical chemokine receptor 2 (ACKR2), also named D6, regulates local levels of
inflammatory chemokines by internalization and degradation. To explore potential anti …

The atypical chemokine receptor ACKR2 is protective against sepsis

V Borges, F Sônego, A Kanashiro, PB Donate, PH Melo… - Shock, 2018 - journals.lww.com
Sepsis is a systemic inflammatory response as a result of uncontrolled infections.
Neutrophils are the first cells to reach the primary sites of infection, and chemokines play a …

Adaptation and constraint in the atypical chemokine receptor family in mammals

L Pan, J Lv, Z Zhang, Y Zhang - BioMed Research International, 2018 - Wiley Online Library
Atypical chemokine receptors (ACKRs) are a subclass of G protein‐coupled receptors
characterized by promiscuity of ligand binding and an obvious inability to signal after ligand …

The neutrophil anti-tumoral response in cancer: role of ACKR2 and chemokine receptors

M Massara - 2018 - tesidottorato.depositolegale.it
Chemokines are key mediators of inflammation and are involved in both extrinsic and
intrinsic pathway of cancer. Their main function is to induce leukocyte migration through the …

[图书][B] CCL3 Augments Antitumor Responses in CT26 by Enhancing Cellular Trafficking and Interferon-Gamma Expression

F Allen - 2018 - search.proquest.com
Cancer evolves and thrives due to the failures of multiple intracellular and extracellular self-
control mechanisms, and as such, often requires a multifaceted approach for complete …