Background: Strong evidence supports the role of both genetic and environmental factors in
pediatric-onset multiple sclerosis (POMS) etiology. Objective: We comprehensively …

Early‐onset (pediatric and adolescent) multiple sclerosis (MS) is a well‐established
demyelinating disease that accounts for approximately 3‐5% of all MS cases. Thus …

Purpose of review This review will examine the current evidence that genetic and/or
epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype …

Abstract Background and Objective Hispanics with multiple sclerosis (MS) present younger
and more often with optic neuritis (ON) as compared to Whites in the western United States …

Genome-wide associations and HLA genotyping have revealed associations between HLA
alleles and susceptibility to primary membranous nephropathy. However, associations with …

Background: There is a pressing need for robust longitudinal cohort studies in the modern
treatment era of multiple sclerosis. Objective: Build a multiple sclerosis (MS) cohort …

Several studies have investigated the association of different HLA antigens with multiple
sclerosis (MS). However, only few studies have considered the association of high …

Objective: The aim of our present study was to analyse the association of HLA-DRB1 and-
DQB1 alleles and genotypes with Multiple Sclerosis (MS) disability progression in a cohort …

Background: Age at symptom onset (ASO) is a prognostic factor that could affect the accrual
of disability in multiple sclerosis (MS) patients. Some factors are known to influence the risk …

Early-onset (pediatric and adolescent) multiple sclerosis (MS) is a chronic autoimmune and
neurodegenerative disorder of the central nervous system, which accounts for 3–5% of all …