Aptamer-guided nanomedicines for anticancer drug delivery
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …
affinity and specificity to a specific target. Taking advantage of such binding properties …
Influence of aptamer-targeted antibiofilm agents for treatment of Pseudomonas aeruginosa biofilms
S Wang, B Mao, M Wu, J Liang, L Deng - Antonie Van Leeuwenhoek, 2018 - Springer
Biofilms are bacterial communities consisting of numerous extracellular polymeric
substances. Infections caused by biofilm-forming bacteria are considered to be a major …
substances. Infections caused by biofilm-forming bacteria are considered to be a major …
Introduction of SELEX and important SELEX variants
Y Dong, Z Wang, S Wang, Y Wu… - Aptamers for Analytical …, 2018 - Wiley Online Library
To screen aptamers with good affinity and specificity for various analytical applications,
conventional SELEX (Systematic Evolution of Ligands by EXponential Enrichment) strategy …
conventional SELEX (Systematic Evolution of Ligands by EXponential Enrichment) strategy …
Selection of aptamers based on geometry
JAA West, BC Satterfield - US Patent 9,938,641, 2018 - Google Patents
Disclosed are methods for performing aptamer preselection based on unique geometry and
the content of stems or loops of the aptamer, which methods are capable of providing …
the content of stems or loops of the aptamer, which methods are capable of providing …
[PDF][PDF] 利用SELEX 技术筛选小檗碱核酸适配体及其亲和力表征
张丽娜， 赵鹏， 田国英， 田平芳 - 北京化工大学学报(自然科学版), 2018 - journal.buct.edu.cn
小檗碱是一种价格低廉且生物安全性良好的小分子化合物, 筛选能与小檗碱互相作用的核酸片段
, 旨在开发新型遗传元件并拓展其在生物技术领域的应用. 利用指数富集的配基系统进化技术 …
, 旨在开发新型遗传元件并拓展其在生物技术领域的应用. 利用指数富集的配基系统进化技术 …
Generation of Aptamers Against Natural Toxins and Their Application as Biosensors
Y Morita, D Fujiwara - Applied RNA Bioscience, 2018 - Springer
RNA or ssDNA aptamers, which are capable of binding to target molecules with high affinity
and specificity, are selected in vitro from large combinatorial nucleic acid libraries by a …
and specificity, are selected in vitro from large combinatorial nucleic acid libraries by a …
Nucleic acid aptamers
P Giangrande, F Miller, W Thiel - US Patent 10,113,172, 2018 - Google Patents
2017-08-28 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …