Stages of dysfunctional decision-making in addiction

A Verdejo-Garcia, TTJ Chong, JC Stout, M Yücel… - Pharmacology …, 2018 - Elsevier
Drug use is a choice with immediate positive outcomes, but long-term negative
consequences. Thus, the repeated use of drugs in the face of negative consequences …

[HTML][HTML] Chronic alcohol exposure disrupts top-down control over basal ganglia action selection to produce habits

R Renteria, ET Baltz, CM Gremel - Nature communications, 2018 - nature.com
Addiction involves a predominance of habitual control mediated through action selection
processes in dorsal striatum. Research has largely focused on neural mechanisms …

Parcellating cognitive heterogeneity in early psychosis-spectrum illnesses: a cluster analysis

JJ Crouse, AA Moustafa, SER Bogaty, IB Hickie… - Schizophrenia …, 2018 - Elsevier
Cognitive impairment is argued to represent a core feature of psychosis-spectrum illnesses.
However, within-diagnosis heterogeneity is common, and risk factors for poor cognition …

[HTML][HTML] Neuropsychological performance in alcohol dependent patients: A one-year longitudinal study

L Ioime, R Guglielmo, GF Affini, M Quatrale… - Psychiatry …, 2018 - ncbi.nlm.nih.gov
Objective Despite several studies that have highlighted the harmful effects of alcohol
consumption on cognitive functions it remains unclear whether certain brain areas are more …

[HTML][HTML] Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

I Bazov, D Sarkisyan, O Kononenko… - Translational …, 2018 - nature.com
Molecular changes in cortical areas of addicted brain may underlie cognitive impairment
and loss of control over intake of addictive substances and alcohol. Prodynorphin (PDYN) …

Profiling online poker players: Are executive functions correlated with poker ability and problem gambling?

M Schiavella, M Pelagatti, J Westin, G Lepore… - Journal of gambling …, 2018 - Springer
Poker playing and responsible gambling both entail the use of the executive functions (EF),
which are higher-level cognitive abilities. This study investigated if online poker players of …

Cognitive deficits in problematic drinkers with and without mild to borderline intellectual disability

N van Duijvenbode, R Didden… - Journal of …, 2018 - journals.sagepub.com
We examined cognitive deficits in problematic drinkers with and without mild to borderline
intellectual disability (MBID). Problematic drinkers were expected to show a significantly …

Decision-making dysfunctions in addiction

A Verdejo-Garcia - The Routledge handbook of philosophy and …, 2018 - taylorfrancis.com
This chapter provides an overview of the decision-making dysfunctions which identified in
people with substance addictions, as compared with non-drug-using groups, via cognitive …

The role of the medial prefrontal cortex in reward seeking: Functional evidence on cellular and molecular mechanisms underlying drug and natural reward seeking

S Pfarr - 2018 - archiv.ub.uni-heidelberg.de
The medial prefrontal cortex (mPFC) is critically involved in cognitive flexibility and top down
control of behavior. Dysfunction of this brain region is a hallmark of many psychiatric …

[图书][B] Effects of Mild Traumatic Brain Injury on Ethanol Consumption and the Combined Effects on Neuroinflammation, Cognition, and Behavior in Mice

JL Hoffman - 2018 - search.proquest.com
The relationship between alcohol consumption and traumatic brain injury (TBI) often focuses
on alcohol consumption increasing the likelihood of incurring a TBI, rather than alcohol use …