Traumatic brain injury (TBI)–induced coagulopathy is a common and well-recognized risk for
poor clinical outcomes, but its pathogenesis remains poorly understood, and treatment …

Background Epistaxis (nosebleed) most commonly affects children and the elderly. The
majority of episodes are managed at home with simple measures. In more severe cases …

The 2 leading causes of death after trauma are blood loss and neurologic injury, which
account for more than three-quarters of injury related mortality. 1 Fifty percent of early deaths …

BACKGROUND: Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize
bleeding in cardiac surgery. Up to 50% cardiac surgical patients have chronic renal …

Objectives: Identify the etiology of hypovolemic shock. Outline the presentation of
hypovolemic shock. List the treatment and management options available for hypovolemic …

Objective Antifibrinolytic agent tranexamic acid (TXA) has a potential clinical benefit for in-
hospital patients with severe bleeding but its effectiveness in pre-hospital settings remains …

The so-called Patient Blood Management (PBM) programmes have been developed around
the world during the last decade. PBM is defined as “the timely application of medical and …

Attention to establishing rapid vascular access and correcting hypothermia and acidosis is
essential. A judicious approach to crystalloid resuscitation in the bleeding pediatric trauma …

Abstract Purpose of Review The present review will cover most recent and important studies
on acute treatment of intracerebral hemorrhage (ICH). Recent Findings Overly pessimistic …

Objective The World Maternal Antifibrinolytic (WOMAN) Trial was the first in the UK to use
the option of waiver of informed consent at the time of an obstetric emergency. This …