Natural products for human health: an historical overview of the drug discovery approaches

S Bernardini, A Tiezzi, V Laghezza Masci… - Natural product …, 2018 - Taylor & Francis
Natural products (NPs) are secondary metabolites produced and used by organisms for
defending or adapting purposes. These molecules were naturally selected during thousands …

[HTML][HTML] Natural products chemistry: The emerging trends and prospective goals

RA Khan - Saudi pharmaceutical journal, 2018 - Elsevier
The role and contributions of natural products chemistry in advancements of the physical
and biological sciences, its interdisciplinary domains, and emerging of new avenues by …

Designing algorithms to aid discovery by chemical robots

AB Henson, PS Gromski, L Cronin - ACS central science, 2018 - ACS Publications
Recently, automated robotic systems have become very efficient, thanks to improved
coupling between sensor systems and algorithms, of which the latter have been gaining …

Current strategies to induce secondary metabolites from microbial biosynthetic cryptic gene clusters

J Begani, J Lakhani, D Harwani - Annals of Microbiology, 2018 - Springer
The genome of actinomycetes and several other microorganisms are endowed with many
cryptic gene clusters that can code for previously undetected, a plethora of complex …

Protective effect of Aurelia aurita against free radicals and streptozotocin-induced diabetes

MR Talluri, A Ketha, GR Battu, RS Tadi… - ||| Bangladesh …, 2018 - bdpsjournal.org
The present work was carried out to identify the antioxidant and anti-diabetic activities of
Aurelia aurita. The chemical profiling analysis showed that it possess different biologically …

Total synthesis of strictamine: a tutorial for novel and efficient synthesis

C Wang, S Zhang, Y Wang, SH Huang… - Organic Chemistry …, 2018 - pubs.rsc.org
When teaching synthetic design in the classroom, the novelty and efficiency of the overall
synthetic route are the key values being imparted to the younger generation of synthetic …

Rapid, field-deployable method for collecting and preserving plant metabolome for biochemical and functional characterization

SA Skubel, V Dushenkov, BL Graf, Q Niu, A Poulev… - PLoS …, 2018 - journals.plos.org
Study of plant metabolome is a growing field of science that catalogs vast biochemical and
functional diversity of phytochemicals. However, collecting and storing samples of plant …

[PDF][PDF] Concentração Inibitória Mínima e atividade antioxidante do extrato de Plectranthus ornatus CODD.(Lamiaceae) extraído por diferentes solventes

BMS Puton, JL Bernardi, CED Oro… - Revista Perspectiva …, 2018 - uricer.edu.br
O objetivo do presente trabalho foi avaliar a concentração inibitória mínima e a atividade
antioxidante dos diferentes extratos de P. ornatus obtidos por extrações sucessivas em …

[PDF][PDF] Diversity and bioactivity of microorganisms associated with Australian stingless bee species

T Mills - 2018 - unsworks.unsw.edu.au
The rapid emergence and transfer of antimicrobial resistance in pathogenic organisms has
greatly reduced our ability to treat clinical microbial infections. To continue to treat clinical …

[图书][B] Methodenentwicklung an der festen Phase: Etablierung neuer Dithian-Linker zur Synthese flexibler Bausteine am Beispiel von neuen fluorierten Verbindungen …

S Susanto - 2018 - books.google.com
In der modernen Wirkstoffforschung stellen die Festphasensynthese und die
Naturstoffsynthese wichtige Methoden dar, um potenzielle Wirkstoffe bereitstellen zu …