Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Dutch
Pharmacogenetics Working Group provide therapeutic recommendations for well‐known …

The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly
used medications. Variation in CYP2D6 is associated with inter-individual differences in …

The enormous successes in the genetics and genomics of many diseases have provided the
basis for the advancement of precision medicine. Thus, the detection of genetic variants …

We investigated whether CYP2D6 extensive metabolizers carrying a nonfunctional allele
are at higher risk of phenoconversion to poor metabolizers in the presence of CYP2D6 …

The findings to date are promising and provide us a better understanding of the
development of side effects and response to antipsychotics. However, more comprehensive …

Personalized or precision medicine is emerging in the treatment of human diseases and
management based on each individual's genetic pattern and response to drugs categorized …

Despite evidence that pharmacogenetics can improve tamoxifen pharmacotherapy, there
are few studies with American Indian and Alaska Native (AIAN) people. We examined …

Scientific curiosity and fascination have played a key role in human research with
psychedelics along with the hope that perceptual alterations and heightened insight could …

American Association of Clinical Chemistry Laboratory Medicine Practice Guideline—Using
Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients | The Journal …