High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen

N Ndjeka, K Schnippel, I Master… - European …, 2018 - Eur Respiratory Soc
South African patients with rifampicin-resistant tuberculosis (TB) and resistance to
fluoroquinolones and/or injectable drugs (extensively drug-resistant (XDR) and preXDR-TB) …

Treatment of drug-susceptible and drug-resistant tuberculosis

JA Caminero, A Scardigli, T van der Werf… - Tuberculosis (ERS …, 2018 - books.google.com
The treatment of TB, both drug-susceptible and drug-resistant forms, should be based on
two principles: 1) the combination of drugs (at least four) to avoid selection pressure …

Adverse Drug Reaction Onsets in Uganda's VigiBase®: Delayed International Visibility, Data Quality and Illustrative Signal Detection Analyses

R Kiguba, HB Ndagije, V Nambasa, SM Bird - Pharmaceutical Medicine, 2018 - Springer
Introduction Developing countries can improve their pharmacovigilance systems by
analysing their own medication safety data. Objective The aims of this study were to …

Revising the definition of extensively drug-resistant tuberculosis

CG Lange, D Chesov, JJ Furin, ZF Udwadia… - The Lancet Respiratory …, 2018 - ibn.idsi.md
Rezumat WHO estimated that in 2017, 460 000 people developed multidrug-resistant (MDR)
tuberculosis, defined by bacillary resistance to rifampicin and isoniazid, the two most …

Better and safer treatment for multidrug-resistant tuberculosis

PE Farmer - The Lancet, 2018 - thelancet.com
levofloxacin, or moxifloxacin. These drugs—unlike the other key drugs recommended for the
treatment of multidrug-resistant tuberculosis—are also supported by evidence from …

Reducing harm in the treatment of multidrug-resistant tuberculosis

A Reuter, J Furin - The Lancet, 2018 - thelancet.com
When describing the profound hearing loss she suffered as a result of her treatment for
multidrug-resistant tuberculosis, the noted advocate Nandita Venkatesan said:“My world fell …

[PDF][PDF] The price of bedaquiline

L McKenna - Treatment Action Group, 2018 - treatmentactiongroup.org
In December 2012, bedaquiline (Sirturo) became the first new tuberculosis (TB) drug from a
new drug class to receive approval by the US Food and Drug Administration (FDA) in 40 …

Treatment outcomes of patients with drug resistant tuberculosis; Experience from a tertiary care hospital in Abbottabad

A Suleman, Z Iqbal, HN Khan, R Ullah - Pakistan Journal of Chest …, 2018 - pjcm.net
Background: The emergence of Drug resistant tuberculosis (DR-TB) challenging all efforts
against TB control and this diseasenowbecameaglobalhealth problem. It isaman …

Introducing molecular testing of pyrazinamide susceptibility improves MDR-TB treatment outcomes: a prospective cohort study

F Sun, Y Li, Y Chen, W Guan, X Jiang… - European …, 2018 - Eur Respiratory Soc
The current treatment for multidrug-resistant tuberculosis (MDR-TB) takes a lengthy period of
18–24 months and has a poor cure rate of 50–60%. A multi-center, prospective cohort study …

[HTML][HTML] Efectos adversos durante el tratamiento de la tuberculosis multifarmacorresistente con linezolid en México

M Félix-Ponce, AI Jiménez-Gracia… - Neumología y cirugía …, 2018 - scielo.org.mx
Introducción: El tratamiento de la tuberculosis multifarmacorresistente (TB-MDR)
tradicionalmente ha sido poco exitoso. Éste es un problema multifactorial en el que influye …