Nonsteroidal antiinflammatory drug resistance in dysmenorrhea: epidemiology, causes, and treatment

FA Oladosu, FF Tu, KM Hellman - American journal of obstetrics and …, 2018 - Elsevier
Although nonsteroidal antiinflammatory drugs can alleviate menstrual pain, about 18% of
women with dysmenorrhea are unresponsive, leaving them and their physicians to pursue …

Pathophysiology of endometriosis-associated pain: A review of pelvic and central nervous system mechanisms

L Coxon, AW Horne, K Vincent - … Practice & Research Clinical Obstetrics & …, 2018 - Elsevier
Although pain is one of the main symptoms women with endometriosis present with, there is
poor correlation between symptom severity and disease burden and the underlying …

Pain chronification: what should a non-pain medicine specialist know?

B Morlion, F Coluzzi, D Aldington… - … medical research and …, 2018 - Taylor & Francis
Objective: Pain is one of the most common reasons for an individual to consult their primary
care physician, with most chronic pain being treated in the primary care setting. However …

Endometriosis alters brain electrophysiology, gene expression and increases pain sensitization, anxiety, and depression in female mice

T Li, R Mamillapalli, S Ding, H Chang… - Biology of …, 2018 - academic.oup.com
Endometriosis is an estrogen-dependent inflammatory disorder among reproductive-aged
women associated with pelvic pain, anxiety, and depression. Pain is characterized by …

The comorbidities of dysmenorrhea: a clinical survey comparing symptom profile in women with and without endometriosis

SF Evans, TA Brooks, AJ Esterman, ML Hull… - Journal of Pain …, 2018 - Taylor & Francis
Purpose Dysmenorrhea is a common disorder that substantially disrupts the lives of young
women. The frequency of 14 associated symptoms both within and outside the pelvis was …

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

R Nilufer, B Karina, C Paraskevi, D Rebecca… - BioRxiv, 2018 - biorxiv.org
Endometriosis is a common complex inflammatory condition characterised by the presence
of endometrium-like tissue outside the uterus, mainly in the pelvic area. It is associated with …

Cancer driver mutations in endometriosis: variations on the major theme of fibrogenesis

SW Guo - Reproductive medicine and biology, 2018 - Wiley Online Library
Background One recent study reports cancer driver mutations in deep endometriosis, but its
biological/clinical significance remains unclear. Since the natural history of endometriosis is …

Fibromyalgia and irritable bowel syndrome in female pelvic pain

CM Johnson, GEH Makai - Seminars in Reproductive Medicine, 2018 - thieme-connect.com
Fibromyalgia and irritable bowel syndrome are common disorders which often coexist in
women with chronic pelvic pain. Like pelvic pain, these disorders describe symptoms …

Psychotherapy with somatosensory stimulation for endometriosis-associated pain: the role of the anterior hippocampus

F Beissner, C Preibisch, A Schweizer-Arau… - Biological …, 2018 - Elsevier
Background Endometriosis is a gynecological disorder affecting 6%–10% of all women in
their reproductive age. There is an emerging view in the literature that psychological trauma …

Progression of structural brain changes in patients with chronic pancreatitis and its association to chronic pain: a 7-year longitudinal follow-up study

J Muthulingam, SS Olesen, TM Hansen… - Pancreas, 2018 - journals.lww.com
Objectives Temporal information about the structural brain changes in chronic pancreatitis
(CP) and its relation to the clinical manifestations is lacking. This study investigated changes …