MicroRNAs as markers of progression in cervical cancer: a systematic review

B Pardini, D De Maria, A Francavilla, C Di Gaetano… - BMC cancer, 2018 - Springer
Background Invasive cervical cancer (ICC) is caused by high-risk human papillomavirus
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …

Influence of age on histologic outcome of cervical intraepithelial neoplasia during observational management: results from large cohort, systematic review, meta …

C Bekos, R Schwameis, G Heinze, M Gaerner… - Scientific reports, 2018 - nature.com
Aim of this study was to investigate the histologic outcome of cervical intraepithelial
neoplasia (CIN) during observational management. Consecutive women with histologically …

Computational identification, characterization and validation of potential antigenic peptide vaccines from hrHPVs E6 proteins using immunoinformatics and …

A Khan, M Junaid, AC Kaushik, A Ali, SS Ali… - PloS one, 2018 - journals.plos.org
High-risk human papillomaviruses (hrHPVs) are the most prevalent viruses in human
diseases including cervical cancers. Expression of E6 protein has already been reported in …

Cervical cancer screening

CM Rerucha, RJ Caro, VL Wheeler - American family physician, 2018 - aafp.org
Screening in women has decreased the incidence and mortality of cervical cancer.
Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas …

Cervical cancer: evaluation and management

J Wipperman, T Neil, T Williams - American family physician, 2018 - aafp.org
Human papillomavirus infection is the precursor for the development of cervical cancer and
is detectable in 99.7% of squamous cell carcinoma and adenocarcinoma cases. Early …

Regulation of cellular metabolism by high-risk human papillomaviruses

I Martínez-Ramírez, A Carrillo-García… - International journal of …, 2018 - mdpi.com
The alteration of glucose metabolism is one of the first biochemical characteristics
associated with cancer cells since most of these cells increase glucose consumption and …

Characteristic of HPV integration in the genome and transcriptome of cervical cancer tissues

W Li, Y Qi, X Cui, Q Huo, L Zhu, A Zhang… - BioMed research …, 2018 - Wiley Online Library
High‐risk HPV is clearly associated with cervical cancer. HPV integration has been
confirmed to promote carcinogenesis in the previous studies. In our study, a total of 285 DNA …

Minor capsid protein L2 polytope induces broad protection against oncogenic and mucosal human papillomaviruses

S Pouyanfard, G Spagnoli, L Bulli, K Balz… - Journal of …, 2018 - Am Soc Microbiol
The amino terminus of the human papillomavirus (HPV) minor capsid protein L2 contains a
major cross-neutralization epitope which provides the basis for the development of a broadly …

Human papillomavirus infections: Epidemiology and disease associations

JM Palefsky, MS Hirsch, A Bloom - Waltham: UpToDate, 2018 - uptodate.com
Papillomaviruses are double-stranded deoxyribonucleic acid (DNA) viruses that constitute
the Papillomavirus genus of the Papillomaviridae family. These viruses are highly species …

Nanobody–antigen conjugates elicit HPV-specific antitumor immune responses

AW Woodham, RW Cheloha, J Ling, M Rashidian… - Cancer immunology …, 2018 - AACR
High-risk human papillomavirus-associated cancers express viral oncoproteins (eg, E6 and
E7) that induce and maintain the malignant phenotype. The viral origin of these proteins …