Hepatitis E virus: advances and challenges

I Nimgaonkar, Q Ding, RE Schwartz… - Nature Reviews …, 2018 - nature.com
At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

EASL Clinical Practice Guidelines on hepatitis E virus infection

HR Dalton, N Kamar, SA Baylis, D Moradpour… - Journal of …, 2018 - Elsevier
Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality,
representing an important global health problem. Our understanding of HEV has changed …

Hepatitis E in high-income countries: what do we know? And what are the knowledge gaps?

L Capai, R Charrel, A Falchi - Viruses, 2018 - mdpi.com
Hepatitis E virus (HEV) is a positive-strand RNA virus transmitted by the fecal–oral route.
HEV genotypes 1 and 2 infect only humans and cause mainly waterborne outbreaks. HEV …

Origin, antigenicity, and function of a secreted form of ORF2 in hepatitis E virus infection

X Yin, D Ying, S Lhomme, Z Tang… - Proceedings of the …, 2018 - National Acad Sciences
The enterically transmitted hepatitis E virus (HEV) adopts a unique strategy to exit cells by
cloaking its capsid (encoded by the viral ORF2 gene) and circulating in the blood as “quasi …

Acute hepatitis E in French patients and neurological manifestations

F Abravanel, J Pique, E Couturier, F Nicot, C Dimeglio… - Journal of Infection, 2018 - Elsevier
Summary Objectives Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide.
However, our understanding of the source of contamination is incomplete and the frequency …

Molecular and serological infection marker screening in blood donors indicates high endemicity of hepatitis E virus in Poland

P Grabarczyk, E Sulkowska, J Gdowska, A Kopacz… - …, 2018 - Wiley Online Library
BACKGROUND Until now, markers of hepatitis E virus (HEV) infection have not been
studied in blood donors throughout Poland, and no acute case of HEV infection has been …

An overview: Rabbit hepatitis E virus (HEV) and rabbit providing an animal model for HEV study

L Wang, L Liu, L Wang - Reviews in medical virology, 2018 - Wiley Online Library
Hepatitis E virus (HEV) is a single‐stranded, positive‐sense RNA virus and the causative
agent of hepatitis E. The virus belongs to genus Orthohepevirus in the family Hepeviridae …

Hepatitis E virus–associated cryoglobulinemia in solid‐organ–transplant recipients

O Marion, F Abravanel, A Del Bello… - Liver …, 2018 - Wiley Online Library
Abstract Background & Aims An association between hepatitis E virus (HEV) infection and
cryoglobulinemia has been suggested. The aims of this study were to assess the prevalence …

Chevrier's Field Mouse (Apodemus chevrieri) and Père David's Vole (Eothenomys melanogaster) in China Carry Orthohepeviruses that form Two Putative Novel Genotypes …

B Wang, W Li, JH Zhou, B Li, W Zhang, WH Yang… - Virologica Sinica, 2018 - Springer
Hepatitis E virus (HEV) is the prototype of the family Hepeviridae and the causative agent of
common acute viral hepatitis. Genetically diverse HEV-related viruses have been detected …

Serological and molecular markers of hepatitis E virus infection in HIV-infected patients in Brazil

AC Ferreira, MS Gomes-Gouvêa, G Lisboa-Neto… - Archives of …, 2018 - Springer
In Brazil, the circulation of hepatitis E virus (HEV) has been demonstrated in distinct groups
of individuals and some animals, but its prevalence among individuals with human …