Leptin and brain–adipose crosstalks
Interactions between the brain and distinct adipose depots have a key role in maintaining
energy balance, thereby promoting survival in response to metabolic challenges such as …
energy balance, thereby promoting survival in response to metabolic challenges such as …
[HTML][HTML] Novel insights into how overnutrition disrupts the hypothalamic actions of leptin
S Fruhwürth, H Vogel, A Schürmann… - Frontiers in …, 2018 - frontiersin.org
Obesity has become a worldwide health problem, but we still do not understand the
molecular mechanisms that contribute to overeating and low expenditure of energy. Leptin …
molecular mechanisms that contribute to overeating and low expenditure of energy. Leptin …
[HTML][HTML] Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity
SJ Lee, G Sanchez-Watts, JP Krieger, A Pignalosa… - Molecular …, 2018 - Elsevier
Abstract Objective Glucagon-like peptide-1 (GLP-1) neurons in the hindbrain densely
innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body …
innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body …
[HTML][HTML] Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
Excess caloric intake results in increased fat accumulation and an increase in energy
expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms …
expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms …
[HTML][HTML] Astragaloside IV prevents obesity-associated hypertension by improving pro-inflammatory reaction and leptin resistance
P Jiang, D Ma, X Wang, Y Wang, Y Bi, J Yang… - Molecules and …, 2018 - Elsevier
Low-grade pro-inflammatory state and leptin resistance are important underlying
mechanisms that contribute to obesity-associated hypertension. We tested the hypothesis …
mechanisms that contribute to obesity-associated hypertension. We tested the hypothesis …
Is leptin resistance the cause or the consequence of diet-induced obesity?
KCG de Git, C Peterse, S Beerens… - International Journal of …, 2018 - nature.com
Background/objectives Obesity is strongly associated with leptin resistance. It is unclear
whether leptin resistance results from the (over) consumption of energy-dense diets or if …
whether leptin resistance results from the (over) consumption of energy-dense diets or if …
The impact of androgen actions in neurons on metabolic health and disease
JJ Morford, S Wu, F Mauvais-Jarvis - Molecular and cellular endocrinology, 2018 - Elsevier
The male hormone testosterone exerts different effects on glucose and energy homeostasis
in males and females. Testosterone deficiency predisposes males to visceral obesity, insulin …
in males and females. Testosterone deficiency predisposes males to visceral obesity, insulin …
Neuronal cAMP/PKA signaling and energy homeostasis
L Yang - Neural Regulation of Metabolism, 2018 - Springer
The brain plays a key role in the regulation of body weight and glucose metabolism.
Peripheral signals including hormones, metabolites, and neural afferent signals are …
Peripheral signals including hormones, metabolites, and neural afferent signals are …
Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in …
K Oishi, C Hashimoto - Chronobiology international, 2018 - Taylor & Francis
Feeding at unusual times of the day is thought to be associated with obesity and metabolic
disorders in both experimental animals and humans. We previously reported that time …
disorders in both experimental animals and humans. We previously reported that time …
Heated humidified high-flow nasal oxygen prevents intraoperative body temperature decrease in non-intubated thoracoscopy
CJ Lai, KC Yeh, ML Wang, WH Tai, YJ Cheng - Journal of anesthesia, 2018 - Springer
Purpose In patients receiving non-intubated video-assisted thoracic surgery (NIVATS),
transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) has been applied …
transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) has been applied …