Interactions between the brain and distinct adipose depots have a key role in maintaining
energy balance, thereby promoting survival in response to metabolic challenges such as …

Obesity has become a worldwide health problem, but we still do not understand the
molecular mechanisms that contribute to overeating and low expenditure of energy. Leptin …

Abstract Objective Glucagon-like peptide-1 (GLP-1) neurons in the hindbrain densely
innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body …

Excess caloric intake results in increased fat accumulation and an increase in energy
expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms …

Low-grade pro-inflammatory state and leptin resistance are important underlying
mechanisms that contribute to obesity-associated hypertension. We tested the hypothesis …

Background/objectives Obesity is strongly associated with leptin resistance. It is unclear
whether leptin resistance results from the (over) consumption of energy-dense diets or if …

The male hormone testosterone exerts different effects on glucose and energy homeostasis
in males and females. Testosterone deficiency predisposes males to visceral obesity, insulin …

The brain plays a key role in the regulation of body weight and glucose metabolism.
Peripheral signals including hormones, metabolites, and neural afferent signals are …

Feeding at unusual times of the day is thought to be associated with obesity and metabolic
disorders in both experimental animals and humans. We previously reported that time …

Purpose In patients receiving non-intubated video-assisted thoracic surgery (NIVATS),
transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) has been applied …