Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible protein
R Sharif, S Bak-Nielsen, J Hjortdal… - Progress in retinal and …, 2018 - Elsevier
Keratoconus (KC) is the most common ectatic corneal disease, with clinical findings that
include discomfort, visual disturbance and possible blindness if left untreated. KC affects …
include discomfort, visual disturbance and possible blindness if left untreated. KC affects …
Genetic aspects of keratoconus: a literature review exploring potential genetic contributions and possible genetic relationships with comorbidities
E Loukovitis, K Sfakianakis, P Syrmakesi… - Ophthalmology and …, 2018 - Springer
Introduction Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial
degenerative disorder that is accompanied by corneal ectasia which usually progresses …
degenerative disorder that is accompanied by corneal ectasia which usually progresses …
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
Intraocular pressure (IOP) is currently the sole modifiable risk factor for primary open-angle
glaucoma (POAG), one of the leading causes of blindness worldwide. Both IOP and POAG …
glaucoma (POAG), one of the leading causes of blindness worldwide. Both IOP and POAG …
The thick and thin of the central corneal thickness in glaucoma
GW Belovay, I Goldberg - Eye, 2018 - nature.com
Central corneal thickness (CCT) is an important parameter in the assessment of any
potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in …
potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in …
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients
Keratoconus is a common degenerative corneal disease that can lead to significant visual
morbidity, and both genetic and environmental factors have been implicated in its …
morbidity, and both genetic and environmental factors have been implicated in its …
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
AI Iglesias, A Mishra, V Vitart, Y Bykhovskaya… - Nature …, 2018 - nature.com
Central corneal thickness (CCT) is a highly heritable trait associated with complex eye
diseases such as keratoconus and glaucoma. We perform a genome-wide association meta …
diseases such as keratoconus and glaucoma. We perform a genome-wide association meta …
A new perspective on the genetics of keratoconus: why have we not been more successful?
H Valgaeren, C Koppen, G Van Camp - Ophthalmic Genetics, 2018 - Taylor & Francis
Twin studies and family studies suggest an important genetic basis for keratoconus (KC).
Involvement and association of several genes with the disease has been reported …
Involvement and association of several genes with the disease has been reported …
The genetics of retinopathy of prematurity: a model for neovascular retinal disease
Topic Retinopathy of prematurity (ROP) is a proliferative retinal vascular disease in
premature infants and is a major cause of childhood blindness worldwide. In addition to …
premature infants and is a major cause of childhood blindness worldwide. In addition to …
Research progress on human genes involved in the pathogenesis of glaucoma
HW Wang, P Sun, Y Chen… - Molecular …, 2018 - spandidos-publications.com
Glaucoma is the leading cause of irreversible blindness globally. It is known that the
incidence of glaucoma is closely associated with inheritance. A large number of studies …
incidence of glaucoma is closely associated with inheritance. A large number of studies …
Biomechanics of the healthy and keratoconic corneas: a combination of the clinical data, finite element analysis, and artificial neural network
Background: Keratoconus is recognized by asymmetrical thinning and bulging of the cornea,
resulting in distortion in the surface of the cornea. Keratoconus also alters the biomechanical …
resulting in distortion in the surface of the cornea. Keratoconus also alters the biomechanical …