Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins

R Guagliardo, J Perez-Gil, S De Smedt… - Journal of Controlled …, 2018 - Elsevier
Pulmonary surfactant (PS) has been extensively studied because of its primary role in
mammalian breathing. The deposition of this surface-active material at the alveolar air-water …

Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy

P Merckx, L De Backer, L Van Hoecke, R Guagliardo… - Acta biomaterialia, 2018 - Elsevier
Despite the many advantages of small interfering RNA (siRNA) inhalation therapy and a
growing prevalence of respiratory pathologies, its clinical translation is severely hampered …

Pulmonary surfactant protein SP‐B promotes exocytosis of lamellar bodies in alveolar type II cells

M Martínez‐Calle, B Olmeda, P Dietl, M Frick… - The FASEB …, 2018 - Wiley Online Library
The release of pulmonary surfactant by alveolar type II (ATII) cells is essential for lowering
surface tension at the respiratory air‐liquid interface, stabilizing the lungs against physical …

Homo-and hetero-oligomerization of hydrophobic pulmonary surfactant proteins SP-B and SP-C in surfactant phospholipid membranes

EJ Cabré, M Martínez-Calle, M Prieto, A Fedorov… - Journal of Biological …, 2018 - ASBMB
Pulmonary surfactant is a lipid/protein mixture that reduces surface tension at the respiratory
air–water interface in lungs. Among its nonlipidic components are pulmonary surfactant …

Quenching of tryptophan fluorescence in a highly scattering solution: Insights on protein localization in a lung surfactant formulation

L Ronda, B Pioselli, S Catinella, F Salomone… - Plos one, 2018 - journals.plos.org
CHF5633 (Chiesi Farmaceutici, Italy) is a synthetic surfactant developed for respiratory
distress syndrome replacement therapy in pre-term newborn infants. CHF5633 contains two …

[PDF][PDF] Homo-and hetero-oligomerization of hydrophobic pulmonary surfactant proteins SP-B and SP-C in surfactant phospholipid membranes Elisa J. Cabré1, Marta …

EJ Cabré - researchgate.net
Pulmonary surfactant is a lipid/protein mixture that reduces surface tension at the respiratory
air-water interface in lungs. Among its non-lipidic components are pulmonary surfactant …

[PDF][PDF] PULMONARY SURFACTANT & DRUG DELIVERY SURFACTANTE PULMONAR Y VEHICULIZACIÓN DE FÁRMACOS

AH Roman - 2018 - docta.ucm.es
The financial support to complete this Thesis was provided by the Spanish Ministry of
Economy and Competitiveness (BIO2012-30733 and BIO2015-67930-R) and Programa de …