Because asthma is a disease that results from host-environment interactions, an approach
that allows assessment of the effect of the environment on the host is needed to understand …

Background A growing body of evidence suggests that the plasma concentration of the
neurofilament light chain (NfL) might be considered a plasma biomarker for the screening of …

Background: Several approaches have been suggested to be useful in the early detection of
colorectal neoplasms. Since metabolites are closely related to the phenotype and are …

Background and Aim: It is increasingly recognized that biomedical research has serious
reproducibility issues, which could be overcome at least in part by standardized processing …

Aims Contrasting findings exist regarding the association between circulating sex hormone-
binding globulin (SHBG) and testosterone levels and type 2 diabetes (T2D) in men. We …

Background: The stability limit of an analyte in a biological sample can be defined as the
time required until a measured property acquires a bias higher than a defined specification …

There is an unmet clinical need for objective biomarkers to monitor disease progression and
treatment response in Huntington's disease (HD). The aim of this review is, therefore, to …

Background: Though blood is an excellent biofluid for metabolomics, proteins and lipids
present in blood can interfere with 1d-1H NMR spectra and disrupt quantification of …

Post-mortem biochemistry of serum markers has been the subject of numerous studies, but
in-situ marker stability after death has not been sufficiently evaluated yet. Such laboratory …

This review summarizes evidence that the impact of protein binding of the activity of
antibiotics is multifaceted and more complex than indicated by the numerical value of protein …