When clarity is crucial: regulating ocular surface immunity
The ocular surface is a unique mucosal immune compartment in which anatomical,
physiological, and immunological features act in concert to foster a particularly tolerant …
physiological, and immunological features act in concert to foster a particularly tolerant …
Diabetic macular oedema: under‐represented in the genetic analysis of diabetic retinopathy
S Broadgate, C Kiire, S Halford… - Acta Ophthalmologica, 2018 - Wiley Online Library
Diabetic retinopathy, a complication of both type 1 and type 2 diabetes, is a complex disease
and is one of the leading causes of blindness in adults worldwide. It can be divided into …
and is one of the leading causes of blindness in adults worldwide. It can be divided into …
[HTML][HTML] MyD88 deficiency protects against dry eye–induced damage
Purpose: Dry eye disease (DED) is a multifactorial disease associated with ocular surface
inflammation. Toll-like receptors (TLRs) are integral in the initiation of inflammatory …
inflammation. Toll-like receptors (TLRs) are integral in the initiation of inflammatory …
[HTML][HTML] Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
P Daull, S Guenin, VH De Almeida, JS Garrigue - Molecular Vision, 2018 - ncbi.nlm.nih.gov
Purpose Preservative-free cationic emulsion-based artificial tears (ATs) or drug vehicles are
innovative eye drop formulations with tear film stabilization and drug delivery properties, and …
innovative eye drop formulations with tear film stabilization and drug delivery properties, and …
Expression and regulation of alarmin cytokine IL-1α in human retinal pigment epithelial cells
ZM Bian, MG Field, SG Elner, VM Elner - Experimental eye research, 2018 - Elsevier
Human retinal pigment epithelial (hRPE) cells play important immune-regulatory roles in a
variety of retinal pathologic processes, including the production of inflammatory cytokines …
variety of retinal pathologic processes, including the production of inflammatory cytokines …
Effects of menthol-containing artificial tears on tear stimulation and ocular surface integrity in normal and dry eye rat models
Purpose: To evaluate the effects of menthol-containing artificial tears on tear stimulation and
ocular surface integrity in normal and dry eye rat models. Methods: A total of 54 male Lewis …
ocular surface integrity in normal and dry eye rat models. Methods: A total of 54 male Lewis …
Glycoprotein 340 in mucosal immunity and ocular surface
Abstract Glycoprotein 340 (Gp340) is an innate immune receptor with well-defined roles in
mucosal tissues. It is a normal component of mucosal fluids such as tears, breast milk, and …
mucosal tissues. It is a normal component of mucosal fluids such as tears, breast milk, and …
[HTML][HTML] Production of interleukin-1β related to mammalian target of rapamycin/Toll-like receptor 4 signaling pathway during Aspergillus fumigatus infection of the …
R Xu, J Lin, GQ Zhao, C Li, CY Che… - International Journal of …, 2018 - ncbi.nlm.nih.gov
AIM To elucidate the effect of rapamycin on regulating the production of interleukin (IL)-1β in
Aspergillus fumigatus (A. fumigatus)-induced keratitis and to verify whether the expression of …
Aspergillus fumigatus (A. fumigatus)-induced keratitis and to verify whether the expression of …
Ocular graft-versus-host disease
PJ Tomlins - 2018 - etheses.bham.ac.uk
Haemopoietic Stem Cell Transplant (HSCT) is used as a treatment for a number of
conditions particularly leukaemias. Following conditioning and HSCT, there is a 'resetting'of …
conditions particularly leukaemias. Following conditioning and HSCT, there is a 'resetting'of …