[HTML][HTML] TRPM family channels in cancer

A Hantute-Ghesquier, A Haustrate, N Prevarskaya… - Pharmaceuticals, 2018 - mdpi.com
Members of the TRPM (“Melastatin”) family fall into the subclass of the TRP channels having
varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being …

[HTML][HTML] Markers of clinical utility in the differential diagnosis and prognosis of prostate cancer

G Kristiansen - Modern Pathology, 2018 - Elsevier
Molecular diagnostics is a rapidly evolving area of surgical pathology, that is gradually
beginning to transform our diagnostical procedures for a variety of tumors. Next to molecular …

[HTML][HTML] Calcium and nuclear signaling in prostate cancer

IV Maly, WA Hofmann - International journal of molecular sciences, 2018 - mdpi.com
Recently, there have been a number of developments in the fields of calcium and nuclear
signaling that point to new avenues for a more effective diagnosis and treatment of prostate …

TRPM8 and prostate: a cold case?

L Noyer, GP Grolez, N Prevarskaya, D Gkika… - … -European Journal of …, 2018 - Springer
While originally cloned from the prostate in 2001, transient receptor potential, melastatin
member 8 (TRPM8) has since been identified as the cold/menthol receptor in the peripheral …

[HTML][HTML] RNA interference-mediated depletion of TRPM8 enhances the efficacy of epirubicin chemotherapy in prostate cancer LNCaP and PC3 cells Corrigendum in …

T Liu, Y Liao, H Tao, J Zeng, G Wang… - Oncology …, 2018 - spandidos-publications.com
Several studies have shown that transient receptor potential cation channel subfamily M
member 8 (TRPM8), which has been regarded as a novel prostate‑specific marker, serves a …

Cancer biomarkers

S Stone, A Gutin, S Wagner, J Reid - US Patent 9,976,188, 2018 - Google Patents
US9976188B2 - Cancer biomarkers - Google Patents US9976188B2 - Cancer biomarkers -
Google Patents Cancer biomarkers Download PDF Info Publication number US9976188B2 …

Regulation of Canonical and Non-Canonical Hippo Pathway Components in Mitosis and Cancer

S Stauffer - 2018 - digitalcommons.unmc.edu
The Hippo pathway is conserved regulator of organ size through control of proliferation,
apoptosis, and stem-cell self-renewal. In addition to this important function, many of the …

Design and synthesis of bioactive small molecules by traditional and innovative methods

T Ciaglia - 2018 - elea.unisa.it
My PhD research plan concerns the exploration of the structural requirements determining
TRPM8 modulation. We prepared a series of N-substituted tryptamines and identified two …