The rate and rhythm of heart muscle contractions are coordinated by the cardiac conduction
system (CCS), a generic term for a collection of different specialized muscular tissues within …

Long QT syndrome, short QT syndrome, Brugada syndrome and catecholaminergic
polymorphic ventricular tachycardia are inherited primary electrical disorders that …

To identify genetic variation underlying atrial fibrillation, the most common cardiac
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …

The mechanisms underlying Ca2+/calmodulin-dependent protein kinase II (CaMKII)-
induced arrhythmias in ischemia-reperfusion (I/R) are not fully understood. We tested the …

In cardiomyocytes, the voltage-gated transient outward potassium current (Ito) is responsible
for the phase-1 repolarization of the action potential (AP). Gain-of-function mutations in …

ABSTRACT Introduction: Brugada syndrome (BrS) is an inherited cardiac arrhythmia
syndrome characterized by ST-segment elevation in right precordial ECG leads and …

Several inherited arrhythmias, including Brugada syndrome and arrhythmogenic
cardiomyopathy, primarily affect the right ventricle and can lead to sudden cardiac death …

The Brugada syndrome is an inherited channelopathy associated with increased risk of
ventricular arrhythmias and sudden death, often occurring during sleep or resting conditions …

Background Atrial arrhythmias, particularly atrioventricular nodal reentrant tachycardia, can
coexist with drug‐induced type 1 Brugada electrocardiogram (ECG) pattern (DI‐Type1‐BrP) …

Brugada syndrome (BrS) is an inherited disease associated with ST elevation in the right
precordial leads, polymorphic ventricular tachycardia (PVT), and sudden cardiac death in …