The past few decades have witnessed a tremendous progress in understanding the biology
of cancer, which has led to more comprehensive approaches for global gene expression …

Cancer research has been heavily geared towards genomic events in the development and
progression of cancer. In contrast, metabolic regulation, such as aberrant metabolism in …

p53 is an important tumor-suppressor protein that is mutated in more than 50% of cancers.
Strategies for restoring normal p53 function are complicated by the oncogenic properties of …

Background: The objective of this study was to examine the prognostic significance of
carbonic anhydrase IX (CAIX), an endogenous marker for tumor hypoxia; the cellular tumor …

Tamoxifen is an effective treatment for estrogen receptor alpha positive (ERa+)-breast
cancer, however patients who received the treatment for five years have greater mortality …

Mitochondria‐eating protein (Mieap), encoded by a p53‐target gene, plays an important role
in mitochondrial quality control (MQC). Mieap has been reported to have a critical role in …

Breast cancer is considered as the most common malignant disease, especially among
Indian women that accounts for the highest rate of morbidity and mortality., and are amongst …

Background The association between p53 protein phosphorylated at serine 15 (Ser15),
serine 20 (Ser20) and ovarian tumor cell sensitivity after chemotherapy was analyzed in …

Tumor heterogeneity has been shown for several cancers including breast cancer (BC).
Despite the fact that expression of tumor markers may change throughout the metastatic …

Background: Breast cancers are heterogeneous, making it essential to recognize several
biomarkers for cancer outcome predictions especially in young women where the classical …