Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis
D van der Woude, AHM van der Helm-van - Best practice & research …, 2018 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation,
which affects approximately 1% of the population. The benefit of early recognition and …
which affects approximately 1% of the population. The benefit of early recognition and …
Triple positivity for anti–citrullinated protein autoantibodies, rheumatoid factor, and anti–carbamylated protein antibodies conferring high specificity for rheumatoid …
MK Verheul, S Böhringer, MAM van Delft… - Arthritis & …, 2018 - Wiley Online Library
Objective In rheumatoid arthritis (RA), anti–citrullinated protein antibodies (ACPA s) and
rheumatoid factor (RF) are commonly used to aid in the diagnosis. Although these …
rheumatoid factor (RF) are commonly used to aid in the diagnosis. Although these …
Bone loss in rheumatoid arthritis: basic mechanisms and clinical implications
J Shim, Z Stavre, EM Gravallese - Calcified Tissue International, 2018 - Springer
Patients with rheumatoid arthritis (RA) have historically developed progressive damage of
articular bone and cartilage, which correlates with disability over time. In addition, these …
articular bone and cartilage, which correlates with disability over time. In addition, these …
Association of high titers of anti-carbamylated protein antibodies with decreased bone mineral density in early arthritis patients
C Regueiro, AM Ortiz, MD Boveda, S Castañeda… - PLoS …, 2018 - journals.plos.org
Rheumatoid arthritis (RA) has a negative impact on bone that is partly mediated by anti-
citrullinated proteins antibodies (ACPA). These antibodies are associated with erosions, and …
citrullinated proteins antibodies (ACPA). These antibodies are associated with erosions, and …
The challenges of early diagnosis and therapeutic prediction in rheumatoid arthritis.
J Zhao, Z Li - International Journal of Rheumatic Diseases, 2018 - search.ebscohost.com
The article highlights the several aspects of early rheumatoid arthritis (RA) including
classification criteria, diagnostic and predictive biomarkers, and precision medicine in RA …
classification criteria, diagnostic and predictive biomarkers, and precision medicine in RA …
The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching
MAM van Delft, MK Verheul, LE Burgers… - …, 2018 - academic.oup.com
Objective To better understand the contribution of autoantibodies in RA and the biology of
their responses, we evaluated the avidity of the anti-carbamylated protein (anti-CarP) …
their responses, we evaluated the avidity of the anti-carbamylated protein (anti-CarP) …
Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis
P Lac, S Saunders, E Tutunea-Fatan, L Barra… - Journal of …, 2018 - Elsevier
Antibodies to proteins/peptides containing citrulline are hallmarks of Rheumatoid Arthritis
(RA). These antibodies are strongly associated with the expression of the Shared Epitope …
(RA). These antibodies are strongly associated with the expression of the Shared Epitope …
Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP …
DM Boeters, LA Trouw… - Arthritis Research & …, 2018 - Springer
Background The presence of autoantibodies is considered an important characteristic of
rheumatoid arthritis (RA); therefore, both anticitrullinated protein antibodies (ACPA) and …
rheumatoid arthritis (RA); therefore, both anticitrullinated protein antibodies (ACPA) and …
Clinical and etiological meaning of anti-carbamylated protein antibodies in rheumatoid arthritis
S Nakabo - Immunological Medicine, 2018 - Taylor & Francis
Several autoantibodies against proteins with post-translational modifications have been
detected in patients with rheumatoid arthritis (RA) and are called anti-modified protein …
detected in patients with rheumatoid arthritis (RA) and are called anti-modified protein …
[PDF][PDF] The combination of three autoantibodies, ACPA, RF and anti-CarP antibodies is highly specific for rheumatoid arthritis: implications for very early identification of …
MK Verheul, S Böhringer… - Arthritis …, 2018 - scholarlypublications …
Objective In rheumatoid arthritis (RA), the autoantibodies anti-citrullinated protein antibodies
(ACPA) and rheumatoid factor (RF) are commonly used to aid RA diagnosis. Although these …
(ACPA) and rheumatoid factor (RF) are commonly used to aid RA diagnosis. Although these …