The association of CCL3 and CCL4 polymorphisms with HCV clearance in Chinese Han population

M Liu, M Yue, Y Yao, F Zang, L Zhuo, J Wu, X Xia… - Gene, 2018 - Elsevier
Aim To explore the association of CCL3 (rs1063340) and CCL4 (rs1049807) polymorphisms
with hepatitis C virus (HCV) clearance and sustained virologic response (SVR). Methods …

IL28B polymorphism predict the response to chronic hepatitis C treatment

A Kandemir, B Ünsal - Pamukkale Medical Journal, 2018 - dergipark.org.tr
Purpose: Hepatitis C is an important medical problem which causes chronic liver disease.
170 million people are believed to be infected throughout the world. While spontaneous …

Nearly neutral evolution in IFNL3 gene retains the immune function to detect and clear the viral infection in HCV

P Singh, JFP Dass - Progress in Biophysics and Molecular Biology, 2018 - Elsevier
IFNL3 gene plays a crucial role in immune defense against viruses. It induces the interferon
stimulated genes (ISGs) with antiviral properties by activating the JAK-STAT pathway. In this …