Emerging evidence suggests that the clinical success of conventional chemotherapy is not
solely attributed to tumor cell toxicity, but also results from the restoration of …

The traditional view holds that apoptosis is non-immunogenic and does not induce an
inflammatory response. However, recent studies have suggested that certain …

The phosphorylation of eIF2α is essential for the endoplasmic reticulum (ER) stress
response, the formation of stress granules, as well as macroautophagy. Several successful …

A thermal “window” of immunogenic cell death (ICD) elicited by nanoparticle‐based
photothermal therapy (PTT) in an animal model of neuroblastoma is described. In studies …

Induction of Immunogenic Cell Death by Chemotherapeutic Platinum Complexes | SpringerLink
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Cancer is evading the host's defense mechanisms leading to avoidance of immune
destruction. During tumor progression, immune-evading cancer cells arise due to selective …

Oncolytic viruses (OVs) are multimodal cancer therapeutics, with one of their dominant
mechanisms being in situ vaccination. There is a growing consensus that optimal cancer …

Programmed necrosis, necroptosis, is considered to be a highly immunogenic activity, often
mediated via the release of damage-associated molecular patterns (DAMPs). Interestingly …

Rationale: Cardenolides have potential as anticancer drugs. 3′-epi-12β-hydroxyfroside
(HyFS) is a new cardenolide structure isolated by our research group, but its molecular …

Hyperthermia is a cancer treatment where tumor tissue is heated to around 40° C.
Hyperthermia shows both cancer cell cytotoxicity and immune response stimulation via …