The Mayo Clinic recently introduced a diagnostic test that quantifies plasma ceramides in
order to identify patients at risk of major adverse cardiac events. By comparing recent …

Cardiometabolic diseases are one of the leading causes for disability and mortality in the
Western world. The prevalence of these chronic diseases is expected to rise even further in …

BACKGROUND. Accumulation of diacylglycerol (DAG) and sphingolipids is thought to
promote skeletal muscle insulin resistance by altering cellular signaling specific to their …

Despite a clear association between type 2 diabetes (T2D) and fracture risk, the
pathogenesis of bone fragility in T2D has not been clearly elucidated. Insulin resistance is …

In the context of type 2 diabetes, inter-individual variability in the therapeutic response of
blood glucose control to exercise exists to the extent that some individuals, occasionally …

The use of consumer-grade wearables for purposes beyond fitness tracking has not been
comprehensively explored. We generated and analyzed multidimensional data from 233 …

Modifiable lifestyle factors, including exercise and activity energy expenditure (AEE), may
attenuate the unfavorable health effects of obesity, such as risk factors of metabolic …

The majority of fat in the human body is stored as triacylglycerols in white adipose tissue. In
the obese state, adipose tissue mass expands and excess lipids are stored in non-adipose …

This study compared the effects of moderate-intensity endurance training and high-intensity
interval training on fiber type-specific subcellular volumetric content and morphology of lipid …

Obesity has been considered to be a chronic disease that requires medical prevention and
treatment. Intriguingly, many factors, including adipose tissue dysfunction, mitochondrial …