Objectives: To describe, with an emphasis on clinical applications, what is known about the
pathophysiology, management, and implications of septic cardiomyopathy in the adult ICU …

Refractory shock is a lethal manifestation of cardiovascular failure defined by an inadequate
hemodynamic response to high doses of vasopressor medications. Approximately 7% of …

Background Septic shock is characterized by dysregulation of the host response to infection,
with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with …

Background: Vasopressor agents could have certain specific effects in patients with
cardiogenic shock (CS) after myocardial infarction, which may influence outcome. Although …

Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic,
cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving …

Abstract Background and purpose The Japanese Clinical Practice Guidelines for
Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of …

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Vasoplegic syndrome, characterized by low systemic vascular resistance and hypotension
in the presence of normal or supranormal cardiac function, is a frequent complication of …

Purpose We set out to summarize the current knowledge on vasoactive drugs and their use
in the management of shock to inform physicians' practices. Methods This is a narrative …

Background Vasopressin is often utilized for hemodynamic support in patients with septic
shock. However, the most appropriate patient to initiate therapy in is unknown. This study …