Mre11-Rad50–dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1
The Mre11-Rad50-Nbs1 (MRN) protein complex and ATM/Tel1 kinase protect genome
integrity through their functions in DNA double-strand break (DSB) repair, checkpoint …
integrity through their functions in DNA double-strand break (DSB) repair, checkpoint …
Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery
G Millan-Zambrano, H Santos-Rosa, F Puddu… - Molecular cell, 2018 - cell.com
In response to genotoxic stress, cells activate a signaling cascade known as the DNA
damage checkpoint (DDC) that leads to a temporary cell cycle arrest and activation of DNA …
damage checkpoint (DDC) that leads to a temporary cell cycle arrest and activation of DNA …